A Case of Schamberg Disease Successfully Treated with Keishibukuryogan Prepared at Hospital Pharmacy / 日本東洋医学雑誌

Schamberg disease is a subtype of idiopathic pigmentary purpura, which manifests with petechiae. It is assumed to be caused by venous microcirculatory disturbance, or an immunological and allergic mechanism. We report a 55-year-old Japanese male with Schamberg disease successfully treated with keishibukuryogan prepared at a hospital pharmacy. The patient had purpuric eruptions in his both lower legs at first, and brownish pigmentation enlarged with purpura. A dermatologist had diagnosed this, from the clinical findings, as Schamberg disease. We administered keishibukuryogan to the patient because his pathological condition was considered as oketsu. In order to improve effectiveness, keishibukuryogan was manufactured according to our own modification. The eruptions have reduced gradually, and about four months later, have mostly resolved. A Kampo therapy utilizing unseiin has been reported to be effective against idiopathic pigmentary purpura in previous studies. We suggest that a Kampo treatment with keishibukuryogan seems to be effective against idiopathic pigmentary purpura through improvements of microcirculation and inflammation.

Study for Clinical Effects of Byakkokaninjinto on the Patients with Atopic Dermatitis / 日本東洋医学雑誌

We medicated14atopic dermatitis patients who had erythema of the face with byakkokaninjinto. Before prescribing byakkokaninjinto for each patient, a questionnaire on their subjective symptoms or constitutions was carried out. Moreover, in order to evaluate the effect of byakkokaninjinto and the transition of subjective symptoms, such as a hot flushes and thirst of the throat, condition diaries were prepared, and the grade of each symptom was scored by the patients themselves during treatment.These results demonstrated that byakkokaninjinto was effective for patients who had severe hot flushes of the face.

A Case of Contact Dermatitis due to Shiun-ko and Taitsu-ko / 日本東洋医学雑誌

A 50-year-old female developed severe dermatitis on her face during topical therapy with Shiun-ko and Taitsu-ko. The skin lesions almost disappeared in two weeks with oral steroid therapy and did not recur. Patch testing showed positive reactions to Shiun-ko, Taitsu-ko and Lithospermi radix, and beeswax, which were constituents of Shiun-ko and Taitsu-ko. The result suggests that the patient was sensitized with these topical medicaments and developed allergic contact dermatitis.