ABSTRACT
Pharmacological studies of vitamin E and vitamin C as antioxidants in patients with Parkinson's disease. Randomized, comparative and categorical study. This study was conducted in the Department of Pharmacology, Faculty of Pharmacy, University of Karachi in collaboration with Jinnah Post Graduate Medical College Hospital and Mamji Hospital from April 11, 2010 to August, 2010. On enrollment each patient received complete physical examination and laboratory tests were performed. All registered patients were advised to attend the respective outpatient department [OPDs] every week and at the end of 3[rd] month at a special counter allocated for the purpose of this study. Evaluation of the subjects was done on Patients Health Questionnaire and Unified Parkinson's disease Rating Scale [UPDRS]. Patients responded to this combination in a very energizing way making them more active, less depressed and motivated. In some patients who were younger around age of 43 [as compared to others