Síndrome do trefinado: relato de caso / Syndrome of Trephined: A Case Report / Syndrome of Trephined: a case report

Síndrome do trefinado é atualmente uma complicação comum na neurotraumatologia, sendo descrita como uma síndrome na qual ocorre deterioração neurológica acompanhada de sinais e sintomas após a remoção de uma parte considerável de osso do crânio, assim como ocorre na hemicraniectomia. Neste artigo, juntamente com a revisão de literatura, será relatado o caso de um paciente adulto, vítima de acidente automobilístico, com história de traumatismo cranioencefálico (TCE) grave que foi submetido à craniectomia terapêutica, cursando com a síndrome do trefinado.

"Syndrome of the Trephined" or "Sinking Skin Flap Syndrome" is an usual syndrome in which neurological deterioration occurs following removal of a large skull bone flap (for example, in descompressive craniectomy). In this article, we will report the case of a 24 years old male, victim of an automobile accident with severe traumatic brain injury (TBI), which developed the Syndrome of the Trephined.

Wild ornamental germplasm exploration and domestication based on biotechnological approaches: In vitro colchicine treatment to obtain a new cultivar of Scoparia montevidiensis

The genus Scoparia is native from Argentina. The diversity of colours and shape of their flowers bestows this genus a very interesting ornamental potential. The purpose of the present study is to explore the Scoparia species germplasm by means of in vitro polyploidization in order to improve their ornamental qualities. Accessions of S. montevidiensis var. montevidiensis, S. montevidiensis var. glandulifera, S. nudicaulis, S. hasleriana and S. dulcis were collected and maintained under greenhouse conditions. The Murashige-Skoog medium, supplemented with 0.25 mg/L BAP was used for the nodal segments multiplication of the five Scoparia species. Except for S. hasleriana, the multiplication rate of the other species ranged between 10 and 12 shoots per explant. The colchicine doses tested with S. montevidiensis were: 0.0; 0.1; 0.05; 0.01 and 0.001% (24 and 48 hrs). From a total of 364 recovered plants, 4 solid tetraploid and 16 chimeras were detected. Significant differences were observed for the size of flower, leaves, and the stem diameter among the tetraploid plants and between them and the control. The tissue culture proved to be a powerful tool both to multiply the Scoparia material incorporated to our germplasm collection and to obtain new improved varieties of this beautiful genus.