1.
Article
in English
| IMSEAR
| ID: sea-157504
Subject(s)
Animals , Antitubercular Agents/toxicity , Chemical and Drug Induced Liver Injury/chemically induced , Chemical and Drug Induced Liver Injury/etiology , Chemical and Drug Induced Liver Injury/therapy , Female , Liver/injuries , Liver/toxicity , Male , Nigella sativa/therapeutic use , Plant Oils/therapeutic use , Rats , Rats, Wistar
2.
Indian J Physiol Pharmacol
;
1998 Apr; 42(2): 299-302
Article
in English
| IMSEAR
| ID: sea-107302
ABSTRACT
Ginseng (Panax ginseng) and Ashwagandha (Withania somnifera) are widely used as geriatric tonics. Both individually have not shown any toxicity on long term administration. Study was planned to assess the safety of the combination by doing subacute toxicity study in rats with 90 days oral administration using three doses. Food consumption, body weight, haematological, biochemical and histopathological parameters were studied. There was significant increase in body weight, food consumption and liver weight, and improved hematopoiesis was observed. Brain, heart, lung, liver, spleen, kidneys, stomach, testis and ovaries were normal on gross examination and histopathologically. Subacute toxicity studies in rats did not reveal any toxicity.
Subject(s)
Administration, Oral , Animals , Anti-Inflammatory Agents, Non-Steroidal/toxicity , Drug Combinations , Eating/drug effects , Female , Hemoglobins/metabolism , Liver/drug effects , Male , Organ Size/drug effects , Panax , Plant Extracts/toxicity , Plants, Medicinal , Rats , Weight Gain/drug effects , Withania
3.
Indian J Physiol Pharmacol
;
1986 Jan-Mar; 30(1): 118-9
Article
in English
| IMSEAR
| ID: sea-107762
Subject(s)
Animals , Body Weight , Estrogens/pharmacology , Female , Organ Size , Plant Extracts/pharmacology , Rats , Uterus/drug effects , Vagina/drug effects
4.
Indian J Physiol Pharmacol
;
1982 Oct-Dec; 26(4): 325-6
Article
in English
| IMSEAR
| ID: sea-108149