ABSTRACT
Background: Antibiotics are commonly used on presumptive basis in treating oro-dental infections in children .These are sparse studies on patients of antibiotics usage including information on choice, processed, outcome assessment. Present study was precisely an assessment of antimicrobial therapy in Pedodontics outpatients of our university hospital focusing on clinical and laboratory application in management .The practical difference in antibiotics usage is described and rationally aspect is discussed. Methods: The study was carried out in pediatric dentistry outdoor patients, faculty of Dental Science, B.H.U, from March 2015 to May 2016 under routine care of Pediatric Dentistry Department. Pediatric age group (3 to 14 years) patients with oral and dental problem requiring use of antimicrobial drug were selected for study. Results: It is clear from above that all three regimen significantly decrease salivary bacterial counts. Oro dental pain/toothache decrease after treatment with cefixime. Conclusion: Antimicrobial chemotherapy of pediatricoro-dental infection is by subjective decision not by definitive microbiological diagnosis.