Head and neck malignancies are mostly from dermatological origin

Head and neck cancer includes epithelial malignancies of the upper aerodigestive tract [UADT], including the paranasal sinuses, nasal cavity, oral cavity, pharynx, and larynx; and, as the sixth most common cancer worldwide, head and neck cancer represents about 6% of solid tumors. Advances in surgery, radiation therapy, and chemotherapy have improved locoregional control, survival, and quality of life. The outcomes of these treatment modalities have shifted the focus of curative efforts from radical ablation to preservation and restoration of function. This evolution has been documented in the pages of Cancer for the past 6 decades. The median age of diagnosis is in the sixth decade of life, and there is a large male-to-female predominance. Although there has been a slight decrease in overall incidence of head and neck cancer over the past two decades, an increase in base of tongue and tonsillar cancer recently has been observed

Primary immuno-deficiencies in pediatrics

Introduction: There are many different types of primary immunodeficiency syndromes, with an overall prevalence of one in every 2,000 children in the United States. These syndromes are broadly classified as B-cell, T-cell, phagocytic, complement, or combined immunodeficiency disorders, mainly affecting children from a very young age

Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE from January 1987 to March 2017. The following search terms were used: immunodeficiency syndromes, B-cell disorder, T-cell disorder, complement disorder, phagocytic diseases, diagnosis of primary immunodeficiency, newborn screening

Aim of the work: In this study we aimed to understand the various common types of primary immunodeficiency syndromes, and also study their diagnosis and screening methods

Conclusion: Early diagnosis with the help of newborn screening and data recording can help in reducing significant mortality and morbidity of children born with such disorders. Primary health care providers and pediatricians must keep a high degree of suspicion as many times the presentation can be subtle

Adult immunization

Background: Immunization recommendations depend on epidemiological factors as well as age, sex, history of previous vaccination, current health status, occupation and lifestyle. Several vaccines are recommended for adults including, tetanus-diphtheria-acellular pertussis, tetanus-diphtheria, influenza, human papillomavirus, varicella, measles, mumps, and rubella, and pneumococcal 13-valent conjugate or pneumococcal 23-valent polysaccharide, and hepatitis. Such diseases have shown dramatic decrease in incidence and mortality after introduction of vaccines

Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 2001, through February 2017. The following search terms were used: adult immunization, adult vaccine, recent vaccine guidelines, preventive medicine, human papillomavirus, MMR, S. pneumoniae, PCV13, PPSV23, hepatitis A, hepatitis B

Aim: In this review, we aimed at reviewing the updates in adult vaccine and their effectivity

Conclusion: Vaccination for adult population has proved to be of extreme importance and has achieved great successes. Combined efforts of patients, physicians, and policy makers are needed to achieve higher levels of success and improve vaccine coverage