Failure to decolonize mupirocin and linezolid resistant MRSA from a patient with necrotizing soft tissue infection

Colonization with methicillin resistant Staphylococcus aureus [MRSA] is considered to be a major risk factor for skin and soft tissue infections. We present a case of a patient suffering from necrotizing soft tissue infection and exposed to multiple antibiotics and developed colonization with linezolid resistant MRSA [LRMRSA]. He could not be decolonized despite prolonged conventional or modified MRSA decolonization protocols