ABSTRACT
Objective: The aim of the study is to assess the effect of tobacco smoking on the risk of nonfatal acute myocardial infarction in young adults less than years
Materials and methods: We conducted a population-based case-control study with 164 occurrence acute myocardial infarction cases [21 women; 143 men], consecutively visited King Abdulaziz hospital, KSA, and 227 controls [81 women; 146 men], From February 2016 till February 2017. All women are non-Saudi women. Odds ratios [OR] and 95% confidence intervals [95%CI] were calculated using unconditional logistic regression
Results: The commonness of present smoking was 81% in male cases and 54% in male controls [OR = 3.59, 95%CI: 2.49, 5.31] and 60% of female cases were smokers compared with 36% of controls [OR = 2.65, 95%CI: 1.40, 4.98]. No interaction was found between current smoking and gender on myocardial infarction risk [P = 0.399]. A dose-effect response was present, the odds favoring myocardial infarction reaching an eight-fold increase for those who smoked >25 cigarettes/day compared with never smokers. The risk estimate for former smokers was similar to never smokers
Conclusions: Tobacco smoking is an important independent risk factor for acute myocardial infarction in young adults, with similar strength of association for both genders