ABSTRACT
Cherubism is a rare hereditary benign fibro-osseous disorder characterised by bilateral swelling of the mandible and/or maxilla with varying severity of involvement. It occurs because of dominant mutations in SH3BP2 gene on the chromosome 4p16.3. On radiography cherubic lesions appear as multilocular cystic radiolucencies in the jaw bones giving a soap bubble appearance. These lesions usually heal by themselves by the time the patient attains puberty. Treatment is necessary only in aggressive cases where there is severe facial deformity or vital functions are hampered. Surgical corrections are preferred when the lesion is in its dormant phase. The aim of the present case report is to illustrate a case of cherubism in a 9-year-old Saudi boy which is a very rare occurrence as only 1 case of cherubism has been reported so far in the Saudi Arabian population (AU)
Querubismo é uma desordem fibro-óssea hereditária rara caracterizada por aumento de volume bilateral da mandíbula e/ou maxila com graus variáveis de severidade. Ocorre devido a mutação dominante no gene SH3BP2 no cromossomo 4p16.3. Radiograficamente as lesões de querubismo aparecem como radiolucência multilocular semelhantes a bolhas de sabão nos ossos maxilares. Geralmente as lesões involuem espontaneamente quando o paciente atinge a puberdade. O tratamento se faz necessário apenas nos casos mais agressivos que demonstram deformidade facial severa ou comprometimento de funções vitais. Correções cirúrgicas são preferíveis quando a lesão está na fase dormente. O objetivo do presente relato é ilustrar um caso de querubismo em um paciente de 9 anos da Arábia Saudita, sendo este um evento raríssimo com apenas um outro caso relatado na população da Arábia Saudita (AU)
Subject(s)
Humans , Child , Congenital Abnormalities , Cherubism , ChromosomesABSTRACT
This investigation was conducted to study the impacts of using sewage sludge at different concentrations (0, 10, 25, 50, 75 percent) in amendment of desert reclaimed soil properties and some physiological aspects in wheat and jews mallow plants. Generally adding sewage sludge to desert soil improved the soil texture, raised the organic matter contents, water holding capacity and lowered pH value. The contents of NPK gradually increased as the ratio of sewage sludge increased. The fresh and dry weights and biosyntheses of pigment contents of the variously treated test plants were increased by increasing the sewage sludge levels in the soil. Also, total carbohydrate and protein contents of sewage sludge-treated test plants were positively affected. With respect to the proline content and total free amino acids, in most cases, it decreased significantly, expect at 75 percent sewage sludge, which was higher than that of other concentrations. Also, the accumulation of metal was generally higher, especially in the root than that in the shoot system in the test plant tissues.
ABSTRACT
Studies have now proved that strict glycaemic control in the management of diabetes has a favourable effect on the final outcome. In this study we had a look at the prevalence of undiagnosed diabetes in hospitalized patients. Over a 12 week period we studied all patients admitted to our hospital [a district general hospital] to try and ascertain the prevalence of undiagnosed diabetes and what further management and follow has been arranged. 5% of the study population had newly discovered hyperglycaemia, 2% had a new diagnosis of diabetes mellitus using the American Diabetes Association guidelines. 17% of the study population were those with a previous diagnosis of diabetes mellitus, higher than that in the general population. Only 35% of the newly diagnosed diabetics were on steroids. 76% of the patients were on inslun while in hospital but only 25% on discharge. Inpatients have a higher prevalence of diabetes than the general population. The inpatient population represents a good opportunity for early detection and management of diabetes and should not be missed