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Egyptian Journal of Hospital Medicine [The]. 2017; 69 (5): 2442-2447
in English | IMEMR | ID: emr-190057

ABSTRACT

Polycystic ovary syndrome [PCOS] is a typical heterogeneous endocrine disorder characterized by irregular menses, polycystic ovaries, and hyperandrogenism. The pervasiveness of PCOS differs relying upon which criteria are utilized to make the diagnosis. Clinical manifestations incorporate oligomenorrhea or amenorrhea, hirsutism, and normally infertility. Risk factors for PCOS in adult women incorporates type I diabetes, type II diabetes, and gestational diabetes. Insulin resistance influences 50%-70% of women with PCOS prompting various comorbidities containing metabolic syndrome, dyslipidemia, diabetes, glucose intolerance, and hypertension. Studies demonstrate that women with PCOS will probably have expanded coronary artery calcium scores and increased carotid intima-media thickness. Mental health disorders comprising anxiety, depression, binge eating disorder and bipolar disorder similarly occur more often in women with PCOS. Weight loss advances menstrual irregularities, symptoms of androgen excess, and infertility. Management of clinical manifestations of PCOS comprises oral contraceptives for menstrual irregularities and hirsutism. Spironolactone and finasteride are used to treat symptoms of androgen excess. Treatment options for infertility include clomiphene, gonadotropins, laparoscopic ovarian drilling, and assisted reproductive technology. Appropriate diagnosis and administration of PCOS is crucial to address patient concerns yet additionally to anticipate future metabolic, endocrine, psychiatric, and cardiovascular complications

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