Isolation and structural elucidation of antifungal compounds from Curcuma amada

Objective: To isolate and identify the antifungal compounds from Curcuma amada. Methods: The antifungal activity was measured by the diameter of colonies grown on Petri dish, microscopic observation, and CLSI microdilution methods. The antifungal compounds were isolated through bioactivity guided purification by using silica gel and high-performance liquid chromatography. Structural identification of the antifungal compounds was conducted using

Tinea pedis: a clinical dilemma in Bangladeshi population

Tinea pedis is an important public health problem because of the increase in immunosuppressive states. Large scale studies in Asia are scarce, and the baseline incidence of tinea pedis is not firmly established. To find out the clinical types of tiena pedis amont the Bangladeshi population. 200 clinically suspected cases of tinea pedis were included in this study. In all cases, samples were collected for KOH microscopy and culture. Clinical pattern and associated relevant factors were noted according to a predetermined protocol. Papulosquamous tinea pedis was the most common clinical pattern in 80 [40%] followed by interteriginous type in 70 [35%] patients. Hyperkeratotic pattern was found less commonly in 45 [22.5%] patients followed by bullous pattern in 5 [2.5%] patients. The incidence of papulosquamous type of tinea pedis is relatively higher among the Bangladeshi population than other countries