Metabolic parameters in response to exercise: a study on patients with uncontrolled and controlled diabetes

The aim of this study was to assess the impact of uncontrolled diabetes on metabolic functions in response to exercise and determine whether or not appropriate control of diabetes could restore an adequate exercise tolerance. The study was conducted on 40 patients with uncontrolled diabetes mellitus. The study showed a significant impairment of the majority of the metabolic capacities in response to exercise in patients with uncontrolled diabetics. After one year of a proper control of the diabetic state, a significant improvement of the metabolic parameters was detected including maximum oxygen uptake. It was concluded that the appropriate control of diabetes improved significantly most of the metabolic functions in response to exercise