Upper Gastrointestinal Symptoms Are More Frequent in Female than Male Young Healthy Japanese Volunteers as Evaluated by Questionnaire

BACKGROUND/AIMS: Upper gastrointestinal symptoms are more frequent and severe in female than in male outpatients in Japan. This study compared the upper gastrointestinal symptoms between healthy male and female young adult volunteers using a questionnaire. METHODS: In total, 581 third-grade medical students at Saga Medical School aged 22 to 30 years underwent upper gastrointestinal endoscopy and completed a questionnaire (frequency scale for symptoms of gastroesophageal reflux disease) from 2007 to 2013. Of these 581 students, 298 who were negative for Helicobacter pylori infection and had no particular lesions on endoscopic examination were enrolled in the present evaluation. A symptom was defined as positive when the subject evaluated the frequency of the symptom as sometimes, often, or always. RESULTS: The subjects comprised of 163 males (average age, 23.7 years) and 135 females (average age, 23.1 years). Upper gastrointestinal symptoms were more frequent in the females (75 of 135, 55.6%) than males (69 of 163, 42.3%; P < 0.05), with a high score for 4 symptoms (bloated stomach, heavy feeling in the stomach after meals, subconscious rubbing of the chest with the hand, and feeling of fullness while eating meals). Of the 144 subjects (69 males and 75 females) who complained of these symptoms, the females complained of dysmotility symptoms more often than did the males, but this was not true for reflux symptoms. CONCLUSIONS: This study suggests that females develop upper gastrointestinal symptoms more frequently than do males among the young healthy Japanese population.

Primary care physician practices, recommendations, and barriers to the provision of routine and voluntary vaccinations in Japan / 日本プライマリ・ケア連合学会誌

<b>Introduction</b> : Recommendations from healthcare providers are considered by vaccinees and their parents when they decide whether to receive an immunization. However, in Japan, the attitudes of primary care physicians toward vaccination are unknown. We assessed some practices and recommendations of, and barriers to, primary care physicians regarding vaccinations in Japan.<br><b>Methods</b> : A self-administered questionnaire was mailed (in 2012) to 3000 randomly selected physician-members of the Japan Primary Care Association. Excluded were physicians within two years after graduation, living abroad or retired. We described respondent practices, recommendations, and barriers to the provision of routine and voluntary vaccinations.<br><b>Results</b> : The overall response rate was 25.8%. The rates at which physicians gave routine and voluntary vaccines in their own practices were 29.0-91.4% and 15.2-89.5%, respectively. The vaccine recommendation rates for routine and voluntary vaccines were 58.2-70.2% and 14.1-50.9%, respectively. The physicians reported that their barriers to recommendation of routine vaccines were vaccination schedule complexity (32.9%), opinions of vaccinees and parents (28.9%), and vaccine safety (27.7%). They also reported that perceived vaccine safety (62.1%), lack of understanding of vaccine-preventable diseases (55.7%), and complexity of vaccine schedules (44.4%) were reasons given by vaccinees and parents for noncompliance. Physicians' barriers to recommendation of voluntary vaccines were cost (45.3%), safety (35.1%), and lack of information (30.1%). They reported that vaccinees and parents expressed concern about cost (61.8%), safety (51.8%), and lack of vaccine information (50.7%).<br><b>Conclusion</b> : We clarified practices, recommendations, and barriers to primary care physicians regarding routine and voluntary vaccination in Japan.

Lifestyle-Related Risk Factors for Total and Cancer Mortality in Men and Women

We conducted a 14−year follow−up study to analyze the hazard ratio(HR) of mortality regarding lifestyle−related factors in Saga Prefecture, Japan. The subjects included 2, 170 people, who were randomly selected from men and women aged from 40 to 69 years old, and who also completed the standardized questionnaire on lifestyle in 1983. Information about death and corresponding data were obtained either by mail and/or through the city offices in 1997. We found that a lower body weight, a lower physical fitness level, not consuming a balanced diet, and cigarette smoking to be significantly elevated risks for all−causes of death in males after adjustment by age and health status. In addition, these results did not change even after excluding subjects for early death. The HR of the female subjects who quit smoking was significantly high, although it changed to insignificant after excluding subjects for early death. These results suggested that being underweight might be an index of a positive risk of death, while maintaining a higher physical fitness level, being careful to consume a more balanced diet, and non smoking all appear to be indexes of a negative risk of death. In addition, these results might also be considered good evidence for improving poor health habits in health promotion activities.