ABSTRACT
Objective: To determine the predictors of prostate cancer at repeat biopsy in patients initially diagnosed with atypical small acinar proliferation [ASAP]
Design: Retrospective study
Setting: Tepecik Training and Research Hospital, Turkey
Subjects: Among 1240 patients, only 54 patients diagnosed with ASAP on initial biopsy underwent repeat biopsy
Intervention: Patients were classified into cancer, benign and ASAP groups according to their final pathological results after repeat biopsy
Main outcome measure: The final pathological results of repeat biopsy were compared according to the clinicobiological features
Results: At the repeat 24 core prostate biopsy, the diagnoses were benign prostate, prostate cancer and ASAP in 26/54 [48.2%], 20/54 [37.03%] and 8/54 [14.8%] patients, respectively. In the cancer, ASAP and benign groups, the mean age was 67.2 +/- 5.4, 56.3 +/- 6.7 and 61.8 +/- 8.5 years, respectively. The cancer detection rate was 37.03%. Except for patient age, we found no clinical or pathological features predicting prostate cancer in patients with ASAP at repeat biopsy
Conclusion: Only the age of the patients is a predictive factor of prostate cancer at repeat biopsy in patients diagnosed with ASAP