ABSTRACT
In this study, we aimed to investigate atrial electromechanical delay [EMD] in patients with psoriasis. A total of 43 patients with psoriasis [26 mild-moderate, 17 severe] and 17 healthy control subjects were enrolled. Patients with psoriasis were divided into two groups: the mild-moderate group and the severe group according to their psoriasis area severity index [PASI] scores. Atrial EMD was measured from the lateral mitral annulus and called 'PA lateral', from the septal mitral annulus, called 'PA septal', and from the right ventricle tricuspid annulus, called 'PA tricuspid'. Atrial EMD was defined as the time interval from the onset of atrial electrical activity [P wave on surface ECG] to the beginning of mechanical atrial contraction [late diastolic A wave]. All three groups were compared with each other, and correlation analysis was performed to investigate the relationship between the PASI score and interatrial EMD. PA lateral was significantly higher in both the mild-moderate psoriasis group and the severe psoriasis group compared to controls [69 +/- 12 and 78 +/- 13 vs. 60 +/- 6 ms; p = 0.001]. Also, PA septal [63 +/- 11 vs. 53 +/- 6 ms; p = 0.005, post hoc analysis] and PA tricuspid [49 +/- 7 vs. 41 +/- 5 ms; p = 0.009, post hoc analysis] were significantly higher in the severe psoriasis group than in the control group. Correlation analysis revealed that the PASI score was well correlated with PA lateral [r = 0.520, p < 0.001], PA septum [r = 0.460, p = 0.002], interatrial EMD [r = 0.371, p = 0.014] and intra-atrial EMD [r = 0.393, p = 0.009]. Atrial EMD was prolonged in patients with psoriasis. The measurement of atrial EMD might be used to determine the risk of development of AF in patients with psoriasis
ABSTRACT
The aim of this study was to evaluate the association of the levels of red blood cell distribution width [RDW] with the severity of atherosclerosis and to determine whether or not the RDW level on admission is an independent predictor of all-cause mortality in patients with non-ST elevation myocardial infarction [NSTEMI]. Materials and A total of 335 consecutive patients with NSTEMI were enrolled in this study. The patients were divided into high [n = 105] and low [n = 230] SYNTAX groups. The high SYNTAX group was defined as patients with a value in the third tertile [SYNTAX score, SXscore >/=12], while the low SYNTAX group was defined as those with a value in the lower 2 tertiles [SXscore <12]. The high RDW group [n = 152] was defined as patients with RDW >14.25% and the low RDW group [n = 183] as those with RDW ?14.25%. All-cause mortality was followed up to 38 months. The mean follow-up period was 18 +/- 11 months. The RDW levels of patients were significantly higher in the high SYNTAX group than in the low SYNTAX group [15.2 +/- 1.8 vs. 14.2 +/- 1.2, p < 0.001]. Pearson's coefficients were used to determine the degree of association between RDW levels and SXscore and also between RDW levels and high-sensitivity C-reactive protein. There was a significant correlation between RDW levels and SXscore [r = 0.460, p < 0.001]. Also, there was a significant correlation between RDW levels and high-sensitivity C-reactive protein [r = 0.180, p = 0.001]. All-cause mortality rate was not significantly different between the high and low RDW groups [log-rank, p = 0.621]. RDW levels were independently associated with high SXscore but were not associated with long-term mortality in NSTEMI patients
Subject(s)
Humans , Male , Female , Middle Aged , Aged , Coronary Artery Disease/blood , Myocardial Infarction/blood , AtherosclerosisABSTRACT
To determine both ventricular functions and tissue Doppler echocardiography [TDE]-derived myocardial performance index [MPI] in patients with coronary artery ectasia [CAE]. Twenty-five patients with CAE [13 men; mean age 57 +/- 9 years] and 25 age- and sex-matched controls without CAE [8 men; mean age 54 +/- 10 years] were enrolled in the study. Left and right ventricular functions were detected using conventional echocardiography and TDE. Left ventricle-lateral wall [0.61 +/- 0.17; 0.50 +/- 0.10, p = 0.02], interventricular septum [0.66 +/- 0.17; 0.52 +/- 0.10, p = 0.007] and mean MPI [0.63 +/- 0.15; 0.51 +/- 0.09, p = 0.004] were increased in the CAE group compared to the control group. Right ventricular MPI was similar in both the CAE and control groups [0.58 +/- 0.18; 0.52 +/- 0.19, p > 0.05]. The findings show that left ventricular MPI is different in CAE patients without obstructive coronary artery disease compared to the normal control group. Also in these patients, right ventricular MPI was similar to the control group