ABSTRACT
Periodontal Regenerative Surgical Procedures are, by definition, supposed to restore all three tooth-supporting tissues i.e. periodontal ligament fibres, alveolar bone and the cementum. In humans, we can now regenerate considerable amounts of alveolar bone, and periodontal ligament with the use of bone graft material and barrier membranes. The purpose of this article is to acquaint the reader with the current trends as well as some new areas along which periodontal regenerative therapy might shape up in the future. Since, some fields are still in their infancy, it can be only envisioned as to how these new fields of science might constantly evolve to redefine periodontal therapy in due time.
Subject(s)
Genetic Therapy , Growth Substances/pharmacology , Humans , Immunologic Factors/pharmacology , Nanotechnology , Periodontium/drug effects , Regeneration/drug effects , Robotics , Stem Cell Transplantation , Tissue Engineering/methods , Tooth/physiologyABSTRACT
This study compared the anti-inflammatory efficacy of Triclosan and Flurbiprofen in a gel form on clinical parameters of moderate gingivitis cases. The study comprised of 100 sites from 16 volunteers and used split mouth technique. 0.3% Triclosan/0.3% Flurbiprofen gels applied intracrevicularly once daily for one week. Clinical parameters like Plaque index, Gingival index and Bleeding index scores were recorded at 0 day, 4th day and 8th day. The obtained results showed significant reductions in clinical parameters from baseline to 8th day. This indicates local delivery of 0.3% Triclosan/0.3% Flurbiprofen gel can be used as an anti-inflammatory agents either alone or as an adjunct to scaling in periodontal therapy.
Subject(s)
Adolescent , Adult , Anti-Infective Agents, Local/administration & dosage , Anti-Inflammatory Agents, Non-Steroidal/administration & dosage , Dental Plaque Index , Female , Flurbiprofen/administration & dosage , Gels , Gingiva , Gingivitis/drug therapy , Humans , Injections , Male , Periodontal Index , Triclosan/administration & dosageABSTRACT
The objective of the present study was to conduct a comparative evaluation of periodontal bone loss surgically and by radiovisiography. This study included 26 subjects with 23 mesial and 20 distal sites. Majority of RVG measurements were marginally higher than surgical values. On drawing a comparison between surgical and RVG bone loss, the difference value was statistically significant. On mesial sites, the 't' value was 4.55 with p < .001 and on distal sites 't' value was 2.79 with p < .02. In total 60% of sites showed a difference of < 0.5 mm between RVG and surgical values, 28% of sites showed values between 0.6-1.0 mm and 12% showed a1 mm difference.