Antimicrobial agents from selected medicinal plants in Libya / 中国结合医学杂志

<p><b>OBJECTIVE</b>To test the in vitro antimicrobial efficacy of water and methanol extracts of 23 plant species that are commonly used in Libyan folk medicine.</p><p><b>METHODS</b>The antimicrobial activity was determined using the well-diffusion method. Four test microorganisms were used namely, Escherichia coli, Salmonella species, Staphylococcus aureus and Bacillus subtilis. The minimum inhibitory concentration (MIC) was determined for the high biologically active crude plant extracts.</p><p><b>RESULTS</b>Among 23 medicinal plants used in the study, only 5 methanolic extracts [Rosmarinus offcinalis L., Carduus marianium L., Lantana camara L., Rhus tripartite (ueria) Grande, and Thymus capitatus (L.) Hoffm (link)] showed the highest antimicrobial activity against Staphylococcus aureus, Bacillus subtilis and Salmonella species, while 22 methanolic and aqueous extracts showed moderate to weak antimicrobial activity on all tested organisms. However 19 of the extracts showed no activity at all against Gram-ve and Gram +ve microorganisms. MIC was found to be 1.25 mg/mL (Thymus capitatus), 3 mg/mL (Rhus tripartite), 4 mg/mL (Carduus marianium), 5 mg/mL (Rosamarinus officinalis) and 5 mg/mL (Lantana camara), respectively.</p><p><b>CONCLUSIONS</b>The present results revealed that, crude methanolic extracts of the investigated Libyan folk medicinal plants exhibited mild to high in vitro antibacterial activities against Gram-positive and Gram-negative microorganisms.</p>

Fatty acid composition of leaf oil and analgesic activity of alcoholic extract of ficus benghalensis leaves

The fatty acid composition of leaf oil of Ficus benghalensis has been determined. The four fatty acids viz. lauric [3.8%], palmitic [63.6%], oleic [32.3%] and linoleic [0.3%] have been identified on the basis of GLC analysis. Further, owing to the vast medicinal importance of Ficus benghalensis, the analgesic activity of alcoholic extract of leaves has been studied and an increase in reaction time as compared to standard pentazocine has been observed

Chemical constituents from the leaves of xylosma longifolium

A new triterpene glycoside has been identified from the leaves of Xylosma longifolium along with three known compounds. Their structures were established using spectral data and chemical evidences

Chemical constituents of flowers of saussurea sacra

From the flowers of Saussurea sacra three phenolic compounds p-hydroxy acetophenone, 3-methoxy kaempferol and acacetin-7-O-neo-hesperidoside have been isolated. Their structures were elucidated by chemical and physical data [IR, [1]H-NMR, [13]CNMR and mass spectra]

new flavone glycoside from bridelia monoica

A new flavone glycoside named as tamarixctin-3-O-arabinoside, along with two known compounds, dimethyl ester of terphthalic acid and naringenin-7-O-alpha-L-rhamnosyl [1?4] rhamnose have been isolated from the leaves of Bridelia monoica

Triterpenoids from acacia tortilis

From the leaves of Acacia tortilis, a new triterpene of lupane series along, with four known triterpenes have been isolated. Their structures were elucidated by chemical and physical data [IR. 1H-NMR, 13C-NMR and Mass spectra]