ABSTRACT
Objective To explore the influencing factors and relationship of serum 25 (OH) D levels between late-term pregnant women and newborns. Methods A total of 600 pregnant women and 600 newborns were selected in Lishui Maternal and Children Health Institution during 2016 and information were collected by questionnaires. Serum 25 (OH) D levels in pregnant women's venous bloods and newborns' cord bloods were tested respectively before and after delivery. Results Serum 25 (OH) D levels in 600 pregnant women's venous bloods before delivery were (36.25 ±14.92) nmol/L and 75.16% (451 pregnant women) had lower serum 25 (OH) D levels. Serum 25 (OH) D levels in newborns' cord bloods after delivery were (29.59±16.13) nmol/L and 82.50% (495 newborns) had lower serum 25 (OH) D levels. The relationship of serum 25 (OH) D levels between pregnant women and newborns was significant (r=0.892, P<0.05) . Vitamin D supplementation during pregnancy in pregnant women (400 IU/d) 25 (OH) D level was higher than those of not (P<0.05) . Serum 25 (OH) D levels of pregnant women were influenced by seasons (P<0.05) as higher in summer and autumn and lower in spring and winter. Conclusion Serum 25 (OH) D levels of pregnant women and newborns in Lishui were lower and different among seasons. Serum 25 (OH) D levels of pregnant women could have influence on serum 25 (OH) D levels of newborns. It should be encouraged to increase vitamin D intakes and outdoor activities, especially in spring and winter.
ABSTRACT
Objective To explore the relationship between the cardiac function of pregnant women with cardiac disease and the level of N -terminal pro -B -type natriuretic peptide (NT -pro -BNP).Methods A total of 74 pregnant women with cardiac disease and 80 healthy pregnant women were enrolled in the study and the NT -pro -BNP was detected and compared.The concentrations of NT -pro -BNP in different trimester were compared among the healthy pregnant women, and the correlation between the cardiac function of pregnant women with cardiac disease and the level of NT -pro -BNP were analyzed.Results The median of concentrations of plasma NT -pro -BNP in pregnant women with cardiac disease was 352.50 pg/mL,which was significantly higher than that in healthy pregnant women 58.00 pg/mL(P <0.01 ).The cardiac function was positively correlated with the level of NT -pro -BNP (P <0.01 ).The concentration of plasma NT -pro -BNP during the late trimester(49.00 pg/mL)was significantly higher than that of the early trimester(49.00 pg/mL) among the healthy pregnant women (P <0.01 ).Conclusion It is of great clinical value for the concentration of plasma NT-pro -BNP in evaluating the cardiac function of pregnant women with cardiac disease,and the pregnancy may influence the cardiac function.