ABSTRACT
【Objective】 To explore the factors influencing newborn birth weight under the universal two-child policy in Xi’an so as to provide information for maternal health. 【Methods】 For this study we selected the mothers who delivered babies at Xi’an Northwest Women’s and Children’s Hospital from May 2018 to November 2019. Their data included maternal demographic characteristics， delivery mode， and infants’ outcomes. Single factor analysis and multi-factor linear regression methods were used to analyze the factors influencing the birth weight of newborns of different age and mothers’ parity after the universal two-child policy. 【Results】 The newborns’ average birth weight was （3 377±449） g. The incidence of low birth weight and macrosomia was 7.4% and 2.5%， respectively. Multivariate linear regression analysis showed that gestational week of delivery （β=0.322， P0.05）. 【Conclusion】 Maternal women should do a good job in pre-pregnancy assessment， control pre-pregnancy weight， and gain reasonable weight during pregnancy. The community and hospitals should strengthen pre-pregnancy health education so as to scientifically and effectively improve maternal and infant outcomes.
ABSTRACT
Objective To quantitatively analyze the difference in retinal thickness of the macular outer nuclear layer (ONL) between high myopia patients and normal subjects using spectral-domain optical coherence tomography (SD-OCT). Methods Seventy-eight participants (78 eyes) were divided into normal control group and high myopia group, according to the spherical equivalent (SE) of each eye. There were 24 cases (24 eyes) in the normal control group (-0. 25 D ～+0. 25 D) and 54 cases (54 eyes) in the high myopia group(SE＜-6. 00 D). The macular retina was scanned using the posterior pole asymmetry analysis mode of the Heidelberg Spectralis (SD-OCT) system and divided into 9 areas according to Early Treatment of Diabetic Retinopathy Study. Quantitative analysis was performed to compare the difference in retinal thickness of the macular ONL in each area between the high myopia and normal control groups. Results The ONL thickness in the central area of the macular retina was significantly higher than that in the superior, nasal, inferior, and temporal areas (P ＜ 0. 001 for all comparisons). The ONL thickness in the inferior area of the macular retina was significantly lower than that in the central, superior, nasal, and temporal areas (P ＜ 0. 001 for all comparisons). In other sub-regions, no difference in the ONL thickness was found. The ONL thickness in the central, superior, nasal, inferior, and temporal areas was significantly lower in the high myopia group than in the normal control group (P ＜ 0. 05 for all comparisons). Conclusion Regional variation is observed in the ONL thickness. The ONL thickness in the macular area of patients with high myopia is thinner.