ABSTRACT
Objective: To establish the quality control standards for Compound Bushen Granule (CBG) (Radix Astagali, Fructus Psoraleae Semen Cuscutae, Fructus Lycii, etc.). Methods: Radix Astragali, Semen Cuscutae, Fructus Lycii in CBG were identified by TLC, and the content of psoralen and isopsoralen were determined by HPLC. Results: Radix Astragali, Semen Cuscutae, Fructus Lycii could be identified by TLC, the psoralen showed a good linear relationship at a range of 0.0153?g～0.230?g, r=0.9999 , the average recovery was 102.4%, and RSD was 2.7%, respectively; the isopsoralen showed a good linear relationship at a range of 0.0183?g～0.275?g, r=0.9999, the average recovery was 102.4%, and RSD was 2.7% , respectively. Conclusion: The method is accurate and can be used for the quality control of Compound Bushen Granule.
ABSTRACT
Objective: To study the mechanism of jindengshanggen (JDSG) oral liquid's anti infectiion effect.Methods: inhibition on bacteria growth, resistance to Escherichia coli endotoxin and measurement of monocytic phagocaryosis in mice were taken. Results: The effects of JDSG oral liquid is probably not due to the inhibition on bacteria growth, but rather due to its stimulation on other anti infection mechanisms in human body. The enhancement of immune response and toxin tolerance may be one of the mechanisms for JDSG oral liquid to cure acute pharynx infection. Conclusions: These results provide a basis for clinical application of JDSG.