ABSTRACT
Background: Smoking induced lung diseases constitute a complex group of disorders, varying from the well-known entity of Chronic Obstructive Pulmonary Disease (COPD) to the more recently described interstitial lung diseases. Aim and objectives: The aim of the study was to delineate the relation between cigarette smoking and the development of interstitial lung disease with declaration of the different types of the interstitial lung associated with smoking. Materials and methods: This was prospective study consisting of patients with smoking history referred to Department of Radiodiagnosis of NRIGH for HRCT with symptoms of progressive dyspnea. Inclusion criteria were smokers with progressive dyspnea, (age range 30-90 years, mean age 54 years ± 8). HRCT was done to all subjects using GE Light Speed Multislice 4 channels. CT scan examination was performed using GE Light Speed Multislice 4 channels present in our radiology department. The examination was done in supine position. A scout was taken with kV 120 and mA 120, then helical scanning was done in caudo-cranial direction to minimize respiration artifacts, using detector row 4, helical thickness 1.25, pitch 1.5:1, speed (mm/rot) 7.5, Detector configuration 4 · 1.25, beam collimation 5.00 mm, interval 1.00, gantry tilt 0.0, FOV depends on the patients’ body build, but is about 35 cm, kV 120–140, mA 120–160, total exposure time about 16 s during breath hold in inspiration. The images acquired were sent to a separate workstation to be processed, manipulated and reconstructed. Reconstruction of the images was done using reconstruction software available at the workstation to attain HRCT axial, coronal and sagittal images. Also mediastinal window images were done for each case. Results: In the present study, the most common seen HRCT pattern was Idiopathic Pulmonary Fibrosis, most affected gender were males and most affected age group was between 60-70 years. Sreedevi Meka, D Ankamma Rao. Role of HRCT in Smoking Related Interstitial Lung Diseases. IAIM, 2019; 6(8): 78-94. Page 79 Conclusion: In the appropriate clinical evaluation and in the presence of typical findings, high - resolution CT plays an essential role in evaluation and definite diagnosis of Smoking Related – Interstitial Lung Disease, and this may obviate further testing. However, lung biopsy may be needed when the high-resolution CT are relatively non-specific or when a confident definitive diagnosis is needed.