1.
Chinese Journal of Clinical Pharmacology and Therapeutics
;
(12): 257-265, 2023.
Article
in Chinese
| WPRIM
| ID: wpr-1014661
ABSTRACT
AIM: To investigate the effect of dapagliflozin on myocardial injury in type 1 diabetes mice and its mechanism. METHODS: Normal C57BL / 6J male mice were randomly divided into normal control group (Control), diabetes cardiomyopathy group (DCM) and dapagliflozin group (DAPA). The model of diabetes was induced by streptozotocin (STZ) and given maintenance feed. DAPA group was given 10 mg · kg