ABSTRACT
Este estudo contou com uma amostra de 110 pacientes epilépticos residentes no Cariri paraibano, tendo sido desenvolvido em três etapas sucessivas. Durante a primeira etapa, aplicou-se a ficha epidemiológica visando identificar fatores de risco associados ao complexo teníase-cisticercose na etiologia da epilepsia dos pacientes. A segunda etapa consistiu em exames imunológicos dos 110 pacientes com a utilização da técnica EITB para a identificação de anticorpos séricos anti-cisticercos, e da técnica ELISA para a presença de antígenos circulantes. Na terceira etapa, treze pacientes com sorologia considerada positiva foram submetidos a exames tomográficos. A partir da aplicação do questionário, foram detectados alguns fatores de risco. A soroprevalência constatada foi 118,2/1000 habitantes. Dos 13 pacientes com sorologia positiva para cisticercose, 46,1 por cento têm lesões sugestivas de cisticercose de localização parenquimatosa. Conclui-se que os municípios estudados apresentam perfil epidemiológico compatível com a ocorrência do complexo teníase-cisticercose e que a cisticercose possivelmente desempenhe papel importante no surgimento da epilepsia nesses pacientes.
Subject(s)
Adolescent , Adult , Animals , Child , Child, Preschool , Female , Humans , Male , Middle Aged , Cysticercosis/complications , Epilepsy/parasitology , Brazil/epidemiology , Cysticercosis/diagnosis , Cysticercosis/epidemiology , Enzyme-Linked Immunosorbent Assay , Epidemiologic Methods , Immunoblotting , Neurocysticercosis/complications , Neurocysticercosis/diagnosis , Neurocysticercosis/epidemiology , Swine , Tomography, X-Ray Computed , Taenia solium/immunologyABSTRACT
Although not considered as an endemic region, the Northeast of Brazil has the necessary conditions for the development of taeniasis-cysticercosis complex. In a previous paper, we demonstrated that Mulungu do Morro municipality, in the State of Bahia, has a high seroprevalence to cysticercosis in epileptic patients. OBJECTIVE: to determine the prevalence of taeniasis and positive cysticercosis serology in the population of Mulungu do Morro. METHOD: blood and stool samples were collected from a random sampling of the population, by family. The identification of antibodies against T. solium cysticerci was made by EITB and T. solium antigens were identified using a polyclonal antibody-capture ELISA. RESULTS: the cysticercosis seroprevalence was 1.6 percent (C.I. = 0.8 to 2.8 percent) and the taeniasis prevalence 4.5 percent (C.I. = 3.0 to 6.5 percent). Seropositivity to cysticercosis was higher among those who lived in a house of a person testing positive for coproantigen, p=0.017. CONCLUSION: our results demonstrate that the taeniasis-cysticercosis complex is endemic in Mulungu do Morro. We believe that all areas in the world with the same socio-economic and sanitary characteristics are likely to have high prevalence of this parasite
Subject(s)
Humans , Male , Female , Infant, Newborn , Infant , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Cysticercosis , Taeniasis , Antibodies, Helminth , Brazil , Cysticercosis , Endemic Diseases , Prevalence , Risk Factors , Seroepidemiologic Studies , Socioeconomic Factors , Urban PopulationABSTRACT
With the aim to study the magnitude of infection by the metacestode of Taenia solium in a population of epileptic patients in the arid region of Bahia, Northeastern Brazil, we examined 200 consecutive cases who attended an ambulatory clinic in the disctrict of Mulungu do Morro. Sixty-six of the patients had a diagnosis of epilepsy. From them 10 (15.2 percent) presented antibodies against a specific fraction of antigens in Western blot, and 4 (6.0 percent) had circulating parasite products, as tested by capture ELISA. Only 1 case was positive for antibodies and antigens. We found that the frequency of seropositivity was related to the time without epileptic seizure. We conclude that cysticercosis is endemic in the region of Mulungu do Morro and that it is related to a benign form of epilepsy
Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Middle Aged , Cysticercosis/epidemiology , Endemic Diseases , Epilepsy/parasitology , Antibodies, Helminth , Blotting, Western , Brazil/epidemiology , Cysticercosis/complications , Cysticercosis/diagnosis , Enzyme-Linked Immunosorbent Assay , Poverty Areas , PrevalenceABSTRACT
Obras descriptivas que muestran los requisitos a seguir para el análisis y estudio de los problemas de salud en México a nivel epidemiológico. En este caso, el cuaderno del Instituto Nacional de Diagnóstico y Referencia Epidemiológicos se dedicó a detallar las normas necesarias para llevar a cabo el análisis microbiológico de la teniasis y cisticercosis. El libro se divide en siete capítulos: 1. Introducción 2. Sobre el parásito 3. Sobre el huésped 4. Sobre la enfermedad 5. Sobre la epidemiología 6. Sobre la inmunología 7. Referencias