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ABSTRACT Introduction Athletes go through psychological wear during competition phases and we should pay attention to the training of athletes' physical quality, in addition to the exercise of the athlete's psychological quality. Objective This study aims to analyze the relationship between the psychological quality of basketball players and their performance in the game. Methods Basketball players volunteer for the experiment with the "Sixteen Personality Factors Test" scale compiled by American psychologist R.B Cartel to conduct a survey questionnaire. The mathematical statistics method to analyze the data of the research results. Results There were significant differences among the athletes in the broad internal attention and attention pictures (P<0.05). The tenacity, self-control, decision and self-confidence of the analyzed basketball players are at the medium-high level. Conclusion There is a positive correlation between basketball players' psychological quality and their athletic performance. Basketball players need to develop self-control and overcome psychological barriers during the game. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.
RESUMO Introdução Os atletas passam por desgastes psicológicos durante as fases de competição e devemos atentar-nos ao treinamento da qualidade física dos atletas, além do exercício da qualidade psicológica do atleta. Objetivo Este estudo tem como objetivo analisar a relação entre a qualidade psicológica dos jogadores de basquetebol e o desempenho no jogo. Métodos Jogadores de basquetebol se voluntariam para o experimento com a escala de "Teste dos Dezesseis Fatores de Personalidade" compilada pelo psicólogo americano R.B Cartel para realizar um questionário de pesquisa. O método de estatística matemática para analisar os dados dos resultados da pesquisa. Resultados Houve diferenças significativas entre os atletas quanto a atenção interna ampla e as imagens de atenção (P<0,05). A tenacidade, autocontrole, decisão e autoconfiança dos jogadores de basquetebol analisados encontram-se no nível médio-alto. Conclusão Há uma correlação positiva entre a qualidade psicológica dos jogadores de basquetebol e o seu desempenho atlético. Os jogadores de basquetebol precisam desenvolver autocontrole e superar barreiras psicológicas durante o jogo. Nível de evidência II; Estudos terapêuticos - investigação dos resultados do tratamento.
RESUMEN Introducción Los atletas pasan por un desgaste psicológico durante las fases de competición y debemos prestar atención al entrenamiento de la calidad física de los atletas, además del ejercicio de la calidad psicológica del atleta. Objetivo Este estudio pretende analizar la relación entre la calidad psicológica de los jugadores de baloncesto y el rendimiento en el juego. Métodos Los jugadores de baloncesto se ofrecen como voluntarios para el experimento con la escala "Sixteen Personality Factors Test" compilada por el psicólogo estadounidense R.B Cartel para realizar un cuestionario de investigación. El método estadístico matemático para analizar los datos de los resultados de la investigación. Resultados Hubo diferencias significativas entre los atletas en cuanto a la atención amplia interna y los cuadros de atención (P<0,05). La tenacidad, el autocontrol, la decisión y la autoconfianza de los jugadores de baloncesto analizados están en el nivel medio-alto. Conclusión Existe una correlación positiva entre la calidad psicológica de los jugadores de baloncesto y su rendimiento deportivo. Los jugadores de baloncesto necesitan desarrollar el autocontrol y superar las barreras psicológicas durante el juego. Nivel de evidencia II; Estudios terapéuticos - investigación de los resultados del tratamiento.
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ABSTRACT Introduction Long-distance running is characterized by high speed and long-term endurance. It belongs to the group of long-duration high-speed sports dominated by long-term continuous muscular activity. Objective Explore the effect of physical training in long-distance running on improving speed and strength in athletes. Methods A total of 40 student-athletes at a university in a particular city were selected as research subjects. The experimental grouping was performed by lottery, with 20 in the control group and 20 in the experimental group. Results After the independent sample t-test, the results exhibited P=0.023, less than 0.05, showing that long-distance running physical training is very effective in improving speed and strength; the baseline performance of the experimental group was slightly lower than that of the control group, after training, the mean score of the students in the experimental group elevated compared with the control group. Conclusion Long-distance running physical training can significantly improve speed and strength. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.
RESUMO Introdução A corrida de longa distância é caracterizada por um alto grau de combinação de velocidade e resistência a longo prazo. Ela pertence ao grupo de esportes de alta velocidade de longa duração, dominado pela atividade muscular contínua de longo prazo. Objetivo Explorar o efeito do treinamento físico em corrida de longa distância sobre a melhoria da velocidade e da força em seus atletas. Métodos Um total de 40 estudantes de atletismo em uma universidade de uma determinada cidade foram selecionados como objetos de pesquisa, e o agrupamento experimental foi realizado por sorteio, com 20 no grupo de controle e 20 no grupo experimental. Resultados Após o teste t de amostra independente, os resultados exibiram P=0,023, menos de 0,05, mostrando que o treinamento físico de corrida de longa distância é muito eficaz para melhorar a velocidade e a força; o desempenho basal do grupo experimental foi ligeiramente inferior ao do grupo controle, após o treinamento, a pontuação média dos alunos do grupo experimental elevou-se em relação ao grupo controle. Conclusão O treinamento físico de corrida de longa distância pode melhorar significativamente a velocidade e a força. Nível de evidência II; Estudos terapêuticos - investigação dos resultados do tratamento.
RESUMEN Introducción Las carreras de larga distancia se caracterizan por un alto grado de combinación de velocidad y resistencia a largo plazo. Pertenece al grupo de deportes de alta velocidad de larga duración en los que predomina la actividad muscular continua de larga duración. Objetivo Explorar el efecto del entrenamiento físico en carreras de fondo sobre la mejora de la velocidad y la fuerza en sus atletas. Métodos Se seleccionó como objeto de investigación a un total de 40 estudiantes de atletismo de una universidad de una ciudad determinada, y el agrupamiento experimental se realizó por sorteo, con 20 en el grupo de control y 20 en el grupo experimental. Resultados Tras la prueba t de muestras independientes, los resultados arrojaron un P=0,023, inferior a 0,05, lo que demuestra que el entrenamiento físico de carrera de larga distancia es muy eficaz para mejorar la velocidad y la fuerza; el rendimiento de partida del grupo experimental fue ligeramente inferior al del grupo de control; tras el entrenamiento, la puntuación media de los alumnos del grupo experimental se elevó en comparación con la del grupo de control. Conclusión El entrenamiento físico de carreras de larga distancia puede mejorar significativamente la velocidad y la fuerza. Nivel de evidencia II; Estudios terapéuticos - investigación de los resultados del tratamiento.
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To explore prescription medication regularity in the treatment of Alzheimer's disease with traditional Chinese medicine(TCM). With Alzheimer's disease or senile dementia as the subject, collecting and sorting out the journal papers in CNKI were collected as the data source to establish the literature research database of Alzheimer's disease prescriptions, and then the association rule analysis, factor analysis and systematic cluster analysis on the included TCM were conducted. Among the 113 prescriptions included in the standard, the single herb Acori Tatarinowii Rhizoma was the most common. The herbs were mainly warm and flat among four pro-perties, mainly sweet, bitter and spicy among five flavors. The drugs were mainly distributed in five internal organs, and the most commonly used drugs were deficiency tonifying drugs as well as blood activating and stasis removing drugs. In the association rule analysis, it was found that there were 6 drug pairs with the highest association strength. Eight common factors were extracted from the factor analysis, and they were classified into 6 categories in the systematic cluster analysis. The results have shown that the overall principles in treating Alzheimer's disease with modern Chinese medicine are tonifying deficiency, invigorating circulation, activating blood and dispelling phlegm.
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Humans , Alzheimer Disease/drug therapy , Data Mining , Drugs, Chinese Herbal/therapeutic use , Medicine, Chinese Traditional , PrescriptionsABSTRACT
Objective::To observe the effect of modified Dihuang Yinzi on the learning and memory ability and on the neurons in CA1 area of hippocampus of rats suffering from vascular dementia. Method::The 84 male SD rats were randomly selected to form the sham operation group of 12 rats, and the other 72 rats were chosen for the vascular dementia model by means of Bivascular occlusion, and among which 60 were chosen randomly into 6 groups of 12 rats, namely, the model group, the nimodipine group (0.011 g·kg-1), and the high, medium and low dose modified Dihuang Yinzi (4.54, 2.27, 1.14 g·kg-1) respectively. After 30 days of continuous gavage, Morris water maze was used to detect the learning and memory ability of rats, hematoxylin eosin (HE) was used to observe the morphological changes of hippocampal CA1 neurons, transmission electron microscopy was used to observe the ultrastructural changes of hippocampal CA1 neurons, TUNEL was used to detect the apoptosis level of hippocampal CA1 neurons, immunohistochemical(IHC) was used to detect the expression level of phosphatidylinositol-3(PI3K), protein kinase B (Akt), Caspase-3 in hippocampal CA1 tissues. Result::Compared with sham operation group, the escape latency of the model group was significantly prolonged, the number of times of crossing the original platform was significantly reduced (P<0.01), the neuronal morphology of hippocampal CA1 area was damaged to varying degrees, the apoptosis rate was significantly increased (P<0.01), the integral optical density and average optical density of PI3K, Akt were significantly reduced (P<0.01), and the integral optical density and average optical density of Caspase-3 were significantly reduced (P<0.01). Compared with model group, the escape latency was shortened (P<0.05, P<0.01), the number of crossing the original platform was increased (P<0.05, P<0.01), the integrated optical density and average optical density of PI3K and Akt were significantly increased (P<0.01), and the integrated optical density and average optical density of Caspase-3 were decreased in different degrees (P<0.05, P<0.01). Conclusion::Modified Dihuang Yinzi can improve the learning and memory ability of vascular dementia model rats and the damaged neurons in the hippocampal CA1 area. The potential mechanism may be related to the activation of PI3K/Akt signal transduction pathway and the inhibition of apoptosis of neurons in hippocampal CA1 area of rats.
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The history of medical development shows that oriental medicine, or traditional medicine, was born through medical practice during the times when science and technology were immature and underdeveloped, whereas with the development of science and technology, Western medicine, or modern medicine, was born through experimental analysis and research. With the development of medicine, the pros and cons of both medical systems become increasingly evident. How to integrate them and learn from each other will be the direction of future development of medicine. The formation and development of integrated medicine will, inevitably, usher in a new era for medicine.
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Humans , Human Body , Integrative Medicine , Medicine, Chinese Traditional , Models, TheoreticalABSTRACT
<p><b>OBJECTIVE</b>To explore the effect of anhydroicaritin phytosomes (AIP) in preventing and treating bone loss and enhancing bone quality in ovariectomized osteoporosis rats.</p><p><b>METHOD</b>Seventy-two SD female rats were randomly divided into 6 groups: the sham group, the model group, the estrogen group and AIP groups (low, middle, high). The sham group was only sham operated, and the remaining five groups were ovariectomized. One week after the ovariectomy, the rats were given 17 beta-estrogen and AIP (15, 30, 60 mg x kg(-1)) for consecutively three months, during which period their serum calcium (s-Ca), serum phosphorus(s-P), alkaline phosphate (ALP), urine calcium (u-Ca), urine phosphorus(u-P), urinary deoxypyridinoline (D-Pyr) and creatinine (Cr) were detected. Subsequently, rats were sacrificed, and their thighbone, second lumbar vertebrate and forth lumbar vertebrate were collected to detect bone mineral density (BMD), bone calcium (b-Ca) and phosphorus (b-P), biomechanical properties and bone histomorphometric parameters.</p><p><b>RESULT</b>Compared with the sham group, the model group showed a significant increase in serum ALP, u-Ca and D-Pyr /Cr, and reduction in BMD of femur, b-Ca and b-P, biomechanical properties (elastic load, maximum load, break load, stiffness), static parameters (total tissue area, trabecular area, trabecular perimeter) and dynamic parameters (% L Pm, BFR/BV and BFR/ TV), with metratrophia. Compared with the model group, ALP high and middle-dose groups and the estrogen group showed a decrease in serum ALP, u-Ca and D-Pyr/Cr, and growth in BMD of femur, b-Ca and b-P, biomechanical properties of the forth lumbar vertebrae (elastic load, maximum load, break load, stiffness), static parameters (total tissue area, trabecular area, trabecular perimeter) and dynamic parameters (% L Pm, BFR/BV and BFR/TV). The beta-estrogen group showed endometrial hyperplasia, whereas AIP groups showed no hyperplastic change.</p><p><b>CONCLUSION</b>AIP could inhibit enhanced bone turnover induced by ovariectomy, improve BMD the biomechanical properties of vertebrae, without any stimulation on uterus.</p>
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Animals , Female , Rats , Benzopyrans , Therapeutic Uses , Bone Density , Calcium , Blood , Osteoporosis , Drug Therapy , Ovariectomy , Phospholipids , Therapeutic Uses , Phosphorus , Blood , Rats, Sprague-DawleyABSTRACT
<p><b>OBJECTIVE</b>To observe the influent of the different components of nourishing kidney herbs on the main items of bone metabolism in osteoporosis rats induced with Dexamethasona(DXM).</p><p><b>METHOD</b>Models of three-month old SD female rats with osteoporosis here made by being fed with low calcium diet (containing calcium 0.2%) and distilled water, and injected with DXM 0.1 mg/100 g weight intramuscularly, twice a week. Then the osteoporosis rats were treated with different components of nourishing kidney herbs, and the change of calcium, phosphate, alkaline phosphatase(ALP), calcitonin(CT), PTH, CT/PTH, estrogen(E2), testosterone(T), T/E2 and bone section and bone quantitative morphology in these osteoporosis rats were observed.</p><p><b>RESULT</b>The total components of nourishing kidney herbs could improve the general condition of osteoporosis rats, decrease PTH, increase CT, estrogen, testosterone, CT/PTH and T/E2. The total components of nourishing kidney herbs could improve osteoporotic state, promote bone formation, and inhibite bone resorption. But no effect of the A, B, C, D components of nourishing kidney herbs on the main items of bone metabolism in osteoporosis rats induced with DXM was found.</p><p><b>CONCLUSION</b>It is possible that the purification and separation of these herbs weaken or destroy the integrative effect of nourishing kidney herbs or destroy effective components of nourishing kidney herbs during the process of purification and separation.</p>