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1.
J Biosci ; 2014 Dec; 39 (5): 859-866
Article in English | IMSEAR | ID: sea-162001

ABSTRACT

Since aspartame (L-aspartyl-L-phenylalanine methyl ester, ASP) is one of the most widely used artificial sweeteners, the aim of the present study was to investigate its effects on serum glucose and lipid levels as well as its effects on oxidative/antioxidative status in erythrocytes of rats. The experiment included two groups of animals: the control group was administered with water only, while the experimental group was orally administered with ASP (40 mg/kg b.w.) daily, for a period of six weeks. When compared with the control group, the group administrated with ASP indicated higher values of serum glucose, cholesterol and triglycerides. Significantly increased concentrations of superoxide anion (O2 •−), hydrogen peroxide (H2O2), peroxynitrite (ОNОО−) and lipid peroxides (LPO) were recorded in the erythrocytes of ASP treated group in comparison to the control group. In the course of chronic ASP administration, the following was observed: the concentration of reduced glutathione (GSH) and the activity of catalase (CAT) increased. Thus, these findings suggest that long-term consumption of ASP leads to hyperglycemia and hyperlipidemia, as well as to oxidative stress in erythrocytes.

2.
Rev. argent. infectol ; 11(4): 3-5, 1998. ilus
Article in Spanish | LILACS | ID: lil-240641

ABSTRACT

La nocardiosis es una infección oportunista localizada o diseminada, que puede comprometer el pulmón, la piel y los tejidos blandos y el sistema nervioso central. Sus agentes etiológicos, pertenecientes al género Nocardia, son bacterias filamentosas que en el examen microscópico directo se tiñen con la coloración de Kinyoun. La disfunción de la inmunidad celular es un factor de riesgo para la adquisición de la enfermedad. Se presenta el caso clínico de un paciente de sexo masculino con nocardiosis pulmonar y enfermedad avanzada debida a HIV-1


Subject(s)
Humans , Male , Adult , AIDS-Related Opportunistic Infections/drug therapy , AIDS-Related Opportunistic Infections/etiology , Nocardia Infections , Nocardia Infections/complications , Nocardia Infections/diagnosis , Nocardia Infections/drug therapy , Acquired Immunodeficiency Syndrome/complications , Argentina
3.
Rev. argent. infectol ; 11(7): 24-6, 1998. ilus
Article in Spanish | LILACS | ID: lil-240649

ABSTRACT

El Rhodococcus es un bacilo gram+, aerobio, inmóvil, que toma la coloración ácido alcohol resistente en forma inconstante. No esporulado e intracelular, origina una zoonosis que en pacientes VIH+ provoca una infección con localización pulmonar y extrapulmonar. En el 80 por ciento de los casos la forma de presentación primaria es la neumonía cavitada. La inmunodeficiencia del huésped, la localización intracelular y un tratamiento insuficiente se relacionan con la recidiva de la infección. Se presentan 2 casos de infección por este microorganismo, en pacientes VIH+ con localización pulmonar y extrapulmonar y en uno de ellos con carácter recidivante


Subject(s)
Humans , Adult , Actinomycetales Infections/physiopathology , AIDS-Related Opportunistic Infections , Rhodococcus/drug effects , Rhodococcus/pathogenicity , Argentina
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