Electronmieroscopic Findings of the Rat Retina Following Intraperitoneal Injection of 2,4-Dichlorophepoxyacetie Acid

2,4-Dichlorophenoxyacetic acid is a component of agent orange, which was spread during Vietnam War. Due to the toxicity of this agent, several diseases may be occuring today, potentially causing social problem. The author tried to take as preliminary information for a further clinical study by examining whether 2,4-dichlorophenoxyacetic acid makes any change in the retina of a white rat histopathologically. The objects were 6 white rats of 200-300 gm in weight. After diluting 40% 2,4dichlorophenoxyacetic acid, it was injected intraperitoneally into the rats at the levels of 5 mg/kg, 10 mg/kg, 15 mg/kg of agent. The eyeballs of the each groups were enucleated on 24 hours and 3 days and examinated with an electron microscope. Histopathological changes in the retina were characterized by the degeneration of the retinal pigment epithelial cells, the photoreceptor cells, and the choriocapillaris. To prove that 2,4-dichlorophenoxyacetic acid injures human retina, experiments with futher various plans and epidemiological surveys should be provided.

Treatment of Dry Syndrome with Removable Intracanalicular Implants

Canalicular occlusion with silicone plug was carried out in 11 patient, 21 eyes with dry eye syndrome and the effect and safety of the procedure were evaulated. Artificial tears were discontinued or frequency of instillation was reduced in 66.6% of eyes after occlusion of canaliculi. There were no stastiscally significant differences in the mean value of B.U.T. and Schirmer test pre-and post-canalicular occlusion. There were no cases of postoperative epophora, allergic reaction and infection.

Simulation of Paralytic Strabismus and Its Surgical Management Using a Mathematical Model of the Eye

We built a mathematical model of the eye based on the method of Robinson and improved it. It was programmed with C language. With this model several types of paralytic strabismus including superior oblique paralysis, oculomotor nerve paralysis and double elevator paralysis were simulated. Then we performed various surgical procedures such as recession, resection of horizontal recti, transposition, myectomy. Scott's procedure on these simulated squints and analyzed the results. We tried to show the usefulness and limitation of simulation.

Simulation of Paralytic Strabismus and Its Surgical Management Using a Mathematical Model of the Eye

We built a mathematical model of the eye based on the method of Robinson and improved it. It was programmed with C language. With this model several types of paralytic strabismus including superior oblique paralysis, oculomotor nerve paralysis and double elevator paralysis were simulated. Then we performed various surgical procedures such as recession, resection of horizontal recti, transposition, myectomy. Scott's procedure on these simulated squints and analyzed the results. We tried to show the usefulness and limitation of simulation.