ABSTRACT
Context: reproductive domains of the Tehran lipid and glucose study [TLGS] are unique in that they provide reliable information on reproduction of an urban population ofWest Asia. The aim of this review is to present the most important reproductive findings of TLGS
Evidence Acquisition: this review is summarizing all articles published in the context of reproductive aspects of TLGS results over the 20-year follow-up. A comprehensive databases search was conducted in PubMed [including Medline], Web of Science and Scopus for retrieving articles on the reproductive histories in context of the TLGS
Results: the mean [SD] age at menarche and menopause was 13 [1.2] and 49.6 [4.5] years respectively. While pills were the most commonly used modern methods at the initiation of TLGS, the prevalence of condoms rose sharply and significantly over the follow up duration. Among women with history of gestational diabetes, the risk of diabetes and dyslipidemia progression were 2.44 and 1.2 fold higher than others. Prevalences of PCOS and idiopathic hirsutism among reproductive age participants of TLGS were 8.5% [95% CI: 6.8% - 10.2%] and 13.0% [95% CI: 10.9% - 15.1%], respectively. Trend of cardio-metabolic risk factors among women with PCOS showed that there were no statistically significant differences between mean changes of each cardio metabolic variables between PCOS and healthy women; PCOS status also significantly associated with increased hazard of diabetes and prediabetes among women aged younger than 40 years [HR: 4.9; 95% CI: 2.5 - 9.3, P value < 0.001]] and [HR: 1.7; 95% CI: 1.1 - 2.6], P value < 0.005], respectively
Conclusions: the population based nature of TLGS provides a unique opportunity for valid assessment of reproductive issues, the results of which could provide new information for modification of existing guidelines
ABSTRACT
Background and objective: Sexual aspect is one of the most important domains of matrimony satisfaction. Sexual satisfaction has an important role in psychological health of women. Hormonal changes that occur in menopausal period can result in decrease of sexual satisfaction. The aim of this study was to assess the effect of Ginkgo biloba extract [GBE] on sexual function in menopausal women
Materials and methods: In this Triple-blind placebo-controlled trial, 80 healthy female volunteers aged 60 - 50 years, attending 3 health-care centers of Tehran University of Medical Sciences [TUMS], were enrolled. The participants received GBE at a dose of 120-240 mg [n = 40] or placebo [n = 40] daily for 30 days. The instrument of this study was the Sabbatsberg Sexual Rating Scale [SSRS] which the part of it subjectively evaluate sexual satisfaction before and after intervention. The results were analyzed by using, Fisher exact test, independent samples test and Mann-Whitney Test which these had done by SPSS software, version of 16
Result: After intervention, the sexual satisfaction had no significant difference between the two groups of Ginkgo biloba and placebo [P = 0.31]. Also there was no significant difference in the sexual satisfaction compared to the results obtained in the previous years [0.96]
Conclusion: In this study using Ginkgo biloba for a month had no effect on sexual satisfaction of menopausal women. With regarded to many factors can be affected sexual function of menopausal women, no efficacy of Ginkgo biloba on sexual satisfaction can be result of no efficacy of it on factors such as psychological factors