Mechanism Study on Chinese Medicine in Treatment of Nodular Goiter / 中国结合医学杂志

Nodular goiter has become increasingly prevalent in recent years. Clinically, there has been a burgeoning interest in nodular goiter due to the risk of progression to thyroid cancer. This review aims to provide a comprehensive summary of the mechanisms underlying the therapeutic effect of Chinese medicine (CM) in nodular goiter. Articles were systematically retrieved from databases, including PubMed, Web of Science and China National Knowledge Infrastructure. New evidence showed that CM exhibited multi-pathway and multi-target characteristics in the treatment of nodular goiter, involving hypothalamus-pituitary-thyroid axis, oxidative stress, blood rheology, cell proliferation, apoptosis, and autophagy, especially inhibition of cell proliferation and promotion of cell apoptosis, involving multiple signal pathways and a variety of cytokines. This review provides a scientific basis for the therapeutic use of CM against nodular goiter. Nonetheless, future studies are warranted to identify more regulatory genes and pathways to provide new approaches for the treatment of nodular goiter.

Progress in psychology of premenstrual syndrome / 医学研究生学报

There is a high incidence of Premenstrual syndrome in childbearing aged women. Its clinical symptoms including affect seriously many aspects of physical and mental health disorder of women, resulting in interpersonal relationship deteriorious, decreased quality of life, and even suicidal tendency. The biochemical mechanism of the disease is complex, but the social psychological factors such as personality and habits have reached a consensus on the induction of the disease, which will be the next research direction. Further research will reveal the pathogenesis of PMS from another angle. Based on the field of psychology, the article reviews the relationship between social psychological factors such as personality, personality and coping style and the occurrence and development of PMS, and the role of psychological interventions in regulating diseases.