ABSTRACT
Objective To discuss interventional treatment technique for benign ureteral strictures. Methods A total of 19 cases with 20 benign ureteral strictures were treated with balloon dilatation and double-pigtail ureteral stent placement. Results Among 19 caces,16 were succeeded in a rate of 84.2%.The three failure cases included one of compression by aberrant vessels,one by compression of fibrous-strings and the last one due to tortuosity of the ureter.Re-examinations,by intravenous urography and B ultrasound were carried out in 16 successors,showed gradually release of hydro-nephrosis and renal function improvement.Iatrogenic foreign body ocurred in 2 cases,caused by the protruding tail of stent which had been taken out under ureteroscopy. Conclusions Interventional technique for benign ureteral strictures possesses adventages with mild injury,simple operation,and a new effective method.
ABSTRACT
Objective To investigate the myocardial injury induced by bile duct obstruction and the protective effects ulinastatin(UTI). Methods Dynamic observation of of the levels of malondialdyhyde(MDA) and superoxide dismutase(SOD) of myocardial tissues, and the levels of serum TBil, alkaline phosphatase(ALP), MB isoenzyme of creatine kinase(CK MB), endotoxin (ET), and tumor necrosis factor(TNF ?) in bile duct obstruction(BLD) rats and UIT treatment rats. The left ventricles of the rats were obtained for light and electronic microscopic observation . Immunohistochemical staining method of ABC used was to locate the expression and distribution of TNF ? in myocardial tissues. Results After ligation of the common bile duct, serum TBIL, ALP, CK MB, ET, TNF ? levels and myocardium MDA gradully increased, while SOD levels gradually decreased, and the expression of TNF ? in myocardium increased. As compared with BDL group at the same phase, in UIT group, serum TBIL, ALP, CK MB, ET, TNF? levels and myocardium MDA in UTI treated groups decreased, while myocardium SOD increased, and the expression of TNF ? in myocardium decreased.Myocardial injuries of bile duct obstruction were aggravated as time progressed, and there were less myocardial injuries in UTI treated groups than in BDL groups at the same stage as shown with light and electronic microscopic observation.Conclusions UTI can effectively protect the myocardium from ET,TNF ? and free radical injury in bile duct obstucion rats.