Application of beta-2 microglobulin determination in ENT tumours

In order to assess the diagnostic value of Beta-2 Microglobulin, we marked p beta -m and assessed its presence by radioimmunoassay method in 30 benign and 30 malignant ENT tumours. The results of these two groups were 2.03 +/- 0.03 micro g/ml and 1.77 +/- 0.06 micro g/ml respectively. The latter was significantly different from the former and the normal controls [2.02+0.67ug/ml] [p<0.01]. We agree that although it is not specific as a tumour marker, it can still furnish some relevant informations in the diagnosis and follow-up in malignant tumour patients