Research progresses of arterial spin labeling imaging in mild cognitive impairment / 中国医学影像技术

Mild cognitive impairment (MCI) is a prodromal stage of Alzheimer's disease (AD), the pathogenesis of AD is still unclear. Cerebral blood flow is an important indicator of brain function. Various causes lead to decreased regional cerebral blood flow (rCBF) and damage brain. Arterial spin labeling (ASL) MRI is an imaging technology that measure rCBF by magnetizing hydrogen protons in labeled arterial blood as endogenous tracers. The progresses of ASL imaging in early diagnosis and monitoring progression as well as evaluation on therapeutic effects of MCI were reviewed in this article.