ABSTRACT
Objective:To investigate the relationship of osteoporotic vertebral body compression fracture(OVCF)with multifidus muscle and intervertebral disc degeneration in the lower lumbar spine and the lumbar-pelvic parameters in elderly women.Methods:Clinical data of a total of 108 elderly women with osteoporosis were retrospectively analyzed.They were divided into the fracture group(n=56)and the control group(n=52)according to the presence of vertebral body compression fractures.Age, body mass index(BMI)and bone mineral density(BMD)were collected in two groups.The angle of pelvic incidence(PI), angle of pelvic tilt(PT), low lumbar lordosis(LLL)and sacral slope(SS)were measured by the standing lumbar lateral X-ray photography.The degree of degeneration of intervertebral disc L 3-S 1 and multifidus muscle were detected by using the lumbar MRI.These parameters were compared between the two groups. Results:The age, BMI and BMD had no significant difference between the two groups( P>0.05). The degree of intervertebral disc degeneration of L 3-L 4 and L 4-L 5 was statistically significant higher in the fracture group than in the control group( Z=-4.656 and -2.675, P=0.000 and 0.007), while the degree of intervertebral disc degeneration of L 5-S 1 had no statistically significant difference between the two groups( Z=-1.784, P=0.075). There were statistically significant higher multifidus muscle degeneration of L 3-L 4 and L 4-L 5 in the fracture group than in the control group( Z=-3.248 and -4.073, P=0.001 and 0.000), while no significant difference between the two groups in multifidus muscle degeneration of L 5-S 1( Z=-1.096, P=0.282). No statistically significant differences were found in PI, PT, SS and LLL between the two groups( t=1.162, 0.827, -0.082 and -0.677, P=0.248, 0.410, 0.935 and 0.500). Conclusions:The degeneration of intervertebral disc and multifidus muscle of L 3-L 4 and L 4-L 5 is positively correlated with OVCF in elderly women.
ABSTRACT
Objective: To investigate the clinical and pathological characteristics of breast intracystic papillary carcinoma (IPC) and discuss its prognosis and treatment. Methods: The clinical and follow-up information of 49 patients with breast IPC was collected to analyze the clinicopathological characteristics and explore the influences on prognosis. Results: The median age of 49 patients with breast IPC was 64 years old (range: 29-79 years). The median follow-up time was 61 months (range: 24-84 months). The 5-year overall survival and disease-free survival rates were 75.0% and 60.6%, respectively. The 5-year overall survival rates of 12 patients receiving breast-conserving surgery and 37 patients receiving mastectomy were 76.9% and 73.8%, respectively (P = 0.935). Conclusion: Breast IPC is a rare breast malignancy and has been perceived to have a good prognosis. Breast-conserving surgery and mastectomy have been utilized in the treatment of breast IPC.
ABSTRACT
ObjectiveTo investigate the influence of perioperative intravenouse nutritional support on the cellular immune function in patients with gastric carcinoma(GC). Methods57 patients with GC were randomly divided into the experimental group(n=28) and the control group(n=29). Patients in the experiment group, intravenous nutrition was given 1 week before operation and the first week after operation. The total lymphocyte count, T cell subgroup(CD3+,CD4+,CD8+)and CD4+/ CD8+ ratio were observed and compared in the 2 groups. Results The cellular immune function of the experimental group was significantly better than that of the control group(P