ABSTRACT
Pear is one of the main fruits with thousands of years of cultivation history in China. There are more than 2000 varieties of pear cultivars around the world, including more than 1200 varieties or cultivars in China (Legrand et al., 2016). Xinjiang Uygur Autonomous Region is an important pear production region in China with 30 of varieties or cultivars. Pyrus sinkiangensis is the most popular variety, which is mainly distributed in Xinjiang (Zhou et al., 2018). Chlorogenic acid (CGA), p-coumaric acid, and arbutin are the main polyphenols in pear fruit, and their levels show great differences among different varieties (Li et al., 2014). CGA is a potential chemo-preventive agent, which possesses many important bioactivities including antioxidant, diabetes attenuating, and anti-obesity (Wang et al., 2021). Therefore, the specific CGA content of a variety is considered the embodiment of the functional nutritional value of pears.
Subject(s)
Chlorogenic Acid , Fruit , Gene Expression Profiling , Pyrus/genetics , TranscriptomeABSTRACT
Membrane separation technology is a major branch in modern separation technology, which is widely applied in chemical, pharmaceutical and other industries. The purpose of this paper is to introduce principle and the application example of the membrane separation technology in medical devices, to analyse the problems existing in the current application, and to discuss the future development direction.
Subject(s)
Equipment and Supplies , Membranes, Artificial , TechnologyABSTRACT
To investigate the mechanism of Herba Epimedii alcoho l extract for imp otence, Giess reagent was used to observe the effect of the alcohol extract of H erba Epimedii in mice and its effect on release of NO fro m human umbilical vein endothelial cells in vitro was also studied. The results showed that alcoh ol extract of Herba Epimdii had no effect on the release of NO. But the serum co llected from the mice after the medication of alcohol extract of Herba Epimedii for 120min and 180min promoted the production of NO, and the reaction reached th e peak at 120 min. It is indicated that the promotion of NO release from endothe lial cells may be one of the mechanisms of Herba Epimedii for impotence.
ABSTRACT
To explore the antihepatotoxic mechanism of alcohol_extract of Xiao Chaihu Decoction (XCD),Giress reagent was used to observe the effect of the sero_alcohol_extract of XCD and alcohol_extract of XCD on the release of NO from mouse peritoneal macrophage in vitro.The results showed that alcohol_extract of XCD had no effect on the release of NO while the production of NO was improved in the cultured peritoneal macrophage after the medication of sero_alcohol_extract of XCD for 120min,180min and 240min.It is indicated that improving the release of NO from macrophage was one of the mechanisms of XCD in counteracting hepatic damage.
ABSTRACT
To investigate the mechanism of Herba Epimedii alcohol extract for impotence, Giess reagent was used to observe the effect of the alcohol extract of Herba Epimedii in mice and its effect on release of NO from human umbilical vein endothelial cells in vitro was also studied. The results showed that alcohol extract of Herba Epimdii had no effect on the release of NO. But the serum collected from the mice after the medication of alcohol extract of Herba Epimedii for 120min and 180min promoted the production of NO, and the reaction reached the peak at 120 min. It is indicated that the promotion of NO release from endothelial cells may be one of the mechanisms of Herba Epimedii for impotence.