ABSTRACT
To evaluate the effect of nicotinic acid in management of retinal vein occlusions [CRVO or BRVO]. This prospective nonrandomized pilot study included 20 patients [21 eyes] with CRVO or BRVO that received nicotinic acid [3 g/day] for 3 months. A complete ophthalmologic examination uncorrected visual acuity [UCVA], best spectacle-corrected visual acuity [BSCVA], testing for a relative afferent pupillary defect [RAPD], slit-lamp examination, gonioscopy, intraocular pressure [IOP] measurement, fundoscopy and fundus photography was performed. Four patients did not appear for follow-up and hypersensitivity reaction to nicotinic acid and severe hyperglycemia happened in two patients. Therefore, the results of treatment in 16 eyes of 15 are reported. These patients had a mean age of 59.56 +/- 11.12 years. The average length of follow-up was 8.6 +/- 2.7 months. The mean BSCVA was 1.56 +/- 0.66 before treatment, 1.38 +/- 0.72 [p>0.05] at one month and 0.88 +/- 0.69 [p<0.01] at three months. The last BSCVA of all 16 eyes averaged 0.97 +/- 0.73 [p<0.01]. All patients had reduction of hemorrhagic events, cotton wool spots, edema in macula and disc, venous tortuosity, and dilation on basis of fundus photographs 3 months after treatment. Nicotinic acid usage provides enough time for development of collateral vessels, by induction of vasodilatation. Nicotinic acid use is tolerable and is related with mild systemic side effects.
Subject(s)
Humans , Male , Female , Niacin , Prospective Studies , Pilot ProjectsABSTRACT
Central serous chorioretinopathy is a common cause of visual morbidity.It is characterized by idiopathic serous retinal detachment in macular orparamacular regions. The symptoms of the CSC include decreased vision,micropsia and metamorphopsia. The prognosis of the disease is good andalmost 90% of patients obtain visual recovery in a few months. However,in less than 5% of patients the chronic disease with poor prognosis isdeveloped.The acceptable approach is to observe patients with acute central serouschorioretinopathy, because central serous chorioretinopathy is selflimited.The pathophysiology of central serous chorioretinopathy is notclear and not well understood. Therefore, various medical treatmentshave been suggested such as propranolol, indomethacin, bevacizumab,acetazolamide, mifepristone, labetalol, etc. However, wait and watchwould be the most recommended management of the central serouschorioretinopathy
ABSTRACT
Ocular emergency is one of the most common problems in the Emergency Department [ED], but a general survey of ocular emergencies has rarely been reported in the literature. This study reviews cases of ocular emergencies presented to the ED of Khatam Hospital [Mashhad] over a 6-months period. A retrospective analysis was done on patients who presented with eye complaints to the ED of Khatam Hospital-Mashhad between March 2007 and August 2007. Ocular diagnoses and hospitalizations due to ocular emergencies in addition to their associated variables were collected and assessed separately. 28,312 patients presented to the ED during the period with eye complaints. The most frequent diagnoses in newly presented patients were grouped as trauma [61%] and inflammatory disorders [22%]. A male to female ratio of about 2.5:1 was assessed. Both genders had the peak age in the third decade. There was a trend toward increased numbers in late spring and early summer. There were a total of 431 cases of hospitalization [1.5% of all presented patients] most of them due to traumatic consequences notably globe rupture [38% of all hospitalizations]. Ocular occupational casualties estimated to be responsible for 43% of all traumatic injuries occurred between 20-59 years of age. Young males were found to run a higher risk of ocular accidents, especially at work. Individuals under 10 years of age estimated to be particularly at risk for severe ocular traumas e.g. eye penetration. Taking more care of these two specially at risk groups and directing protectional educations and preprations towards their work and play could be suggested