ABSTRACT
Aims: To study the prevalence of infertility in obese or overweight females and its association with Dyslipidemia and Diabetes mellitus. Materials And Methods: The study was performed on 160 infertile women between age 18-45 years who attended Obstetrics and Gynaecology OPD and Medicine OPD in Swaroop Rani Hospital, Prayagraj.The duration of study was from December 2019 to March 2021.Patients were divided into lean/normal weight females and obese/overweight females based on BMI. Results: Out of total 200 patients 40 were excluded and remaining 160 were divided in two groups, Group 1: lean or normal weight infertile women(N1 =63) and Group 2: obese /overweight infertile women(N2= 97) Mean age of controls and cases were found to be comparable(31.54±2.82 vs 31.22±2.97 years) with p =0.50. Mean BMI of control group was found to be 20.23±1.39 kg/m2 as compared to cases with mean BMI 27.77±2.86 kg/m2 which was signi?cantly higher with p=<.001. Mean W:H ratio in cases and controls was found to be 0.83±0.05 and o.74±0.04 respectively with p-value= <0.001. Mean A1C levels in cases was signi?cantly higher than in the control group (5.91±0.91% vs 4.61±0.58%) with p=<.001. Mean S, Triglycerides levels in cases was signi?cantly higher than in the control group. (160.4±96.9 vs 110.2±15.8) with p=<.001. Mean S.Cholesterol levels in cases was signi?cantly higher than in the control group. (165.1±41.06 vs 100±22.1) with p=<.001. Mean S.VLDL levels in cases was signi?cantly higher than in the control group (43.9±18.94 vs 54.9±14.07) with p=<.001.Mean S.LDL levels in cases was signi?cantly higher than in the control group (64.16±22.4 vs 54.33±16.17) with p=<.002. Mean S.HDL levels in control was higher than in the case group. (78.65±6.86 vs 40.77±12.83) with p=<.001. Conclusion: The prevalence of obesity in infertile females at a tertiary care centre was 60.62 %. Positive association of obesity was found with dyslipidemia and diabetes mellitus(A1C -5.91±0.91% vs 4.61±0.58% with p=<.001)in obese females. Most of the females were in the range of impaired glucose tolerance phase which could be reversed by dietary modi?cation and early intervention.