ABSTRACT
Maternal hypothyroidism is known to be associated with adverse perinatal outcomes. This study was done to evaluate the normal reference range of TSH in pregnant women. 483 pregnant women on their first visit to Obstetrics OPD in Era's Lucknow Medical College and hospital were tested for TSH and TPO antibody using ELISA method. 25 out of 483 were positive for TPO Antibody. Of the remaining 458 patients, 142 were in first trimester, 222 were in second trimester and 94 were in third trimester. The TSH values ranged from 0.043 mIU/L to 10.1 mIU/L (mean = 2.34 mIU/L). The reference range of TSH values in all the trimesters are, 0.35 to 5.82(1st trimester), 0.28 to 5.82(2nd trimester) and 0.11 to 6.8(3rd trimester). The reference range of TSH values among the normal pregnant women of Lucknow and its surrounding areas were found to be higher than those recommended by the test kit
ABSTRACT
Diabetes mellitus and thyroid hormone dysfunction are two common endocrinopathies seen in adult population. Insulin and thyroid hormones are intimately involved in cellular metabolism, so excess or deficit of any of them can derange the function of another. To see the prevalence of hypothyroidism in type 2 Diabetes Mellitus patients. Atotal of 235 patients with diagnosed Type 2 Diabetes Mellitus of either sex, aged >20 years were included in the study. Analysis of serum TSH by ELISAwas done in all patients of the study. Atotal of 235(107 males and 128 females) Type 2 Diabetes Mellitus patients were included in the study. Hypothyroidism was seen in 48(20.4%) patients. Hyperthyroidism was seen in 17(7.2%) patients. Euthyroid patients were 170(72.3%). Out of 128 females 27(11.4%) had hypothyroidism whereas out of 107 males 21(8.9%) had hypothyroidism. We conclude that prevalence of hypothyroidism was 20.4% and seen more in female Type 2 Diabetic patients as compared with male patients
ABSTRACT
This study had designed, to explore prevalence of obesity and overweight, on two criteria, Indian and World Health Organization (W.H.O.), amongst students and staff of Era's Lucknow Medical College & Hospital, Lucknow and Era Institute of Health Sciences and Research, Lucknow. As well as, assessment of association of oxidative stress with obesity. MBBS, Nursing and DMLT students as well as Hospital Laboratory Services (HLS) staff had included in this study. Study had carried out in Department of Biochemistry with collaboration of Department of Physiology and HLS. Results of this study had showed that, prevalence of obesity and overweight were high in staff with respect to students. The levels of reduced glutathione (GSH) were decreased in obese with respect to normal; on the other hand Malondialdehyde (MDA) levels were increased in obese with respect to normal.