ABSTRACT
To assess the in vivo treatment of cutaneous leishmaniasis using certain medicinal agents and non medicinal agents in Gezira State, Sudan. To evaluate the in vivo anti-lesihmanial activity of certain plant extracts that used traditionally in Sudan [Azadirachta indica [neem], Accacia nilotica [garad], Allium sativa [garlic, Thoum]]. A total of 72 cases with cutaneous leishmanisis were studied in Wad Madani Dermatology Teaching Hospital [September 1999 - December 2000]. They were from different parts of the Gezira state. The patients were interviewed and examined followed a special designed questionnaire. The cases showed different types of lesions with different duration and appeared in different areas of the body. The cases divided equally into six main groups [12 for each] for treatment with different agents including medicinal agents and plant methanol extracts