Comparative study of congenital malformation between naturally conceived children and those after IVF

To detect and assess any difference that might exist as regards the overall and specific congenital malformation rates between children born after IVF and naturally conceived children. We compared overall and specific congenital malformation rates calculated for IVF children [n =170 naturally conceived children [n = 600] using records from the KAUH the years 2000-2002 controlling for confounding maternal factors. After correction for differences in maternal age, parity between the IVF and control population the OR was 1, 03 [95% CI: 0.86-1.23]. The crude OR for IVF children appeared higher for the cardiovascular organ system and for several specific minor congenital malformations. However, these could be chance findings due to comparison of many malformation categories or may result from remaining differences in ascertaining malformations between IVF and naturally conceived children. The small increase in overall congenital malformations observed in the IVF children appears to be attributable to differences in maternal characteristics

Anatomic and radiologic study of renal vascular anomalies of living and cadaveric renal donors

The aim of this study was to evaluate the importance of accurate preoperative assessment of renal arterial and venous variants. This study included 30 living donors and 10 cadavers were candidates for kidney donation. The living donors were evaluated by Dual-phase multi-detector row CT of the kidneys, while the cadavers were dissected for kidney vasculature anomalies. Renal artery anomalies were detected in 3 living donors while renal vein and renal artery anomalies were detected in 2 cadavers. Knowledge of the venous anatomy prior to laparoscopic surgery is important to avoid vascular injuries and bleeding. The appropriate venous structures, including renal veins, adrenal veins, gonadal veins, and lumbar veins, must be identified and localized

Detection of E. histolytica, G. lamblia and Cryptosporidium copro-antigens in stool samples

A double antibody sandwich ELISA technique using a chromatography purified anti sera against E. histolytica, G. lamblia and Cryptosporidium antigens was applied to detect coproantigens of the corresponding parasites in 90 patients. All positive cases were diagnosed by a parasitological examination and proved to have the infection. In addition to the 90 positive cases, 30 age-matched controls were included in the study, of which 20 individuals were infected with other parasites, but not Cryptosporidium, E. histolytica or G. lamblia [acted as an infected control group] and the other 20 individuals with no intestinal parasites [normal control group]. The assay could detect 100% of those infected with both of G. Lamblia and E. Histolytica and 96.6% of patients with Cryptosporidium infection. False positive reactions were detected in three cases using G. lamblia antisera [92.5%], five cases using E. histolytica antisera [87.5%] and two cases using Cryptosporidium antisera [95%]. A direct increase in the mean antigen level was observed with the increasing intensity of infection in the three parasites; so, higher mean OD reading was observed in the heavily infected cases than the moderately infected ones than lighter intensity of infection. Only those in the elder age group [>20 years] infected with E. Histolytica had statistically higher OD readings of the antigen than the middle age group [10-20 years]. On the other hand, no statistically significant difference was observed between the different age groups and antigen level in cases with either G. lamblia or Cryptosporidium

Bacteriological studies of bronchoalveolar lavage [BAL] in patients with intrinsic asthma

Forty eight patients with intrinsic asthma were investigated by culturing their sputa and BAL quantitatively. A variety of organisms were isolated from these specimens. The rate of isolation of organisms incriminated in precipitating episodes of intrinsic asthma was higher from BAL than from sputum. Oropharyngeal contaminants were successfully bypassed in BAL cultures. A cut off value of 103 colony forming units [cfu]/ml in BAL was found to be useful in diagnosing organisms known to exacerbate asthma. It appears from the study that BAL cultures are more advantageous than sputum cultures Document 5 TI1 CA-125, CA 19-9 and CEA in benign gynecologic tumors: Effect of surgery ABST The present study showed that combining serum essay of CA125, CA19-9 and CEA is useful in the preoperative exclusion of malignancy in patients with ovarian tumors. A leiomyomas were associated with low levels of the 3 tumor markers, elevated levels particularly of serum CA125 may point to adenomyosis in patients with uterine mass. The results showed that the serum levels of the tumor markers were significantly decreased postoperatively. So, it can be safely assumed that the specificity of these tumor markers is not affected by abdominal surgery