ABSTRACT
Background: Congenital heart disease is the most prevalent form of primary congenital disability in newborns and is the leading cause of death in children with congenital malformations. It occurs in approximately 0.8% of live births. With advances in both palliative and corrective surgery, the number of children with congenital heart disease surviving to adulthood has increased dramatically . Tetralogy of Fallot [TOF] is one of the conotruncal family of heart lesions in which the primary defect is an anterior deviation of the infundibular septum [the muscular septum that separates the aortic and pulmonary outflows]
Objective: To revise patients with tetralogy of Fallot [TOF] underwent palliative or total corrective surgical repair in Madinah, Saudi Arabia
Methods: retrospective study was approved from the institutional review board of Madinah cardiac center and abandoned the need for patient consent. Patient Demographic data and procedure details were retrieved from the hospital information system [HIS]. From 2014 till end of 2017, 72 patients had the diagnosis of TOF [ICD 10 code, Q21.3]. Twelve patients were excluded from them. Thus, 60 patients were left as the study cohort. Fifty four patients had total repair from the start [Group I], 3 patients had initial palliative procedure [group II] and 3 patients had both initial palliative procedure then later total repair. All patients from 1 day to less than 14 years are included. All data were analyzed using GraphPad prism version 5.00 for windows
Results: 61.67% of our patients were males, and 38.33% were females with the ratio of 1.6 [Male: Female]. Six [10%] cases were subjected to a palliative correction surgery [group I] and 57 [95%] cases were subjected to total repair surgery [group II]. 11 [18.3%] cases had post-operative complications, 2 [18.2%] cases from group I and 9 [81.8%] cases from group II. Regarding to the type of surgery there was no statistically significant difference between gender and pre and post-operation stay. Also no significance with length of stay, re-intervention, mortality and complications. While there was a significant correlation between age, weight, RPA and LPA
Conclusion: In our cohort of TOF patients the incidence of the disease was higher among males than females. The continuous follow up was highly recommended for TOF patients. The outcomes of surgical treatment including palliative, total and intervention correction surgeries was a complete recovery of 28.33% of studied patients, and the remaining [71.67%] had post-surgical complications
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Objectives: Neonatal sepsis is clinical syndrome of bacteremia with systemic signs and symptoms. Neonatal sepsis is still a leading cause of mortality in neonatal intensive care units all over the world. Early diagnosis and treatment of the newborn infant with suspected sepsis are essential to prevent severe and life threatening complications
Objective: The aim of this study was to evaluate polymorph nuclear [PMN] leucocyte elastase as a diagnostic tool in neonatal sepsis
Subjects and Methods: This study was conducted on 45 full term and preterm neonates suspected as neonatal sepsis compared to 45 apparently healthy neonate with matched age and sex, as a control group
Results: 55.6% of our patients group were full-term patients and 44.4% were preterm. All the patients were subjected to full history taking, full clinical examination, lab investigation including CBC, CRP, blood culture and sensitivity, and measurement of serum polymorph nuclear leucocyte elastase enzyme
Conclusion: Significant elevation of serum polymorph nuclear leucocyte elastase level in neonatal sepsis with high specificity
ABSTRACT
The ability of benzothiadiazole (BTH) and/or humic acid (HA) used as seed soaking to induce systemic resistance against a pathogenic strain of Fusarium oxysporum was examined in four soybean cultivars under greenhouse conditions. Alone and in combination the inducers were able to protect soybean plants against damping-off and wilt diseases compared with check treatment. These results were confirmed under field conditions in two different locations (Minia and New Valley governorates). The tested treatments significantly reduced damping-off and wilt diseases and increased growth parameters, except the number of branches per plant and also increased seed yield. Application of BTH (0.25 g/L) + HA (4 g/L) was the most potent in this respect. Soybean seed soaking in BTH + HA produced the highest activities of the testes of oxidative enzymes followed by BTH in the four soybean cultivars. HA treatment resulted in the lowest increases of these oxidative enzymes. Similar results were obtained with total phenol but HA increased total phenol more than did BTH in all tested cultivars.
Subject(s)
Fusarium , Phenol , Plants , Seeds , Glycine max , Sprains and Strains , Testis , ThiadiazolesABSTRACT
It has been reported that the cannulation of coronary sinus [CS] from the femoral approach is safer than the traditional subclavian approach but is associated with a lower rate of success. We aimed to test the validity of this claim. We evaluated retrospectively 1320 consecutive patients who underwent electrophysiological study [EPS] or ablation over a period of three years using a prospectively collected data. In cases requiring CS cannulation, it was attempted first from the femoral approach, switching if necessary to a subclavian approach when the femoral route failed. Out of 1320 patients, 1165 [88.3%] required CS cannulation. The CS was successfully cannulated from the femoral approach in 99.3% of the cases in which it was attempted. One patient [0.09%] developed transient first degree atrioventricular block during an ablation procedure for AV nodal re-entrant tachycardia during cannulation of the CS that resolved within 3 min. Femoral access failed in 8 patients. In 4 of these cases, the procedure was concluded using CS cannulation via subclavian or jugular venous access. In the other 4 cases, the procedure was concluded successfully without CS cannulation, including an AF ablation in which CS cannulation proved impossible by either subclavian or femoral approach. Femoral access can be used for CS cannulation with a high rate of procedural success in the vast majority of patients undergoing EPS and ablation. This approach is safe, and associated with a high rate of procedural success
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Tuberculosis [TB] is responsible for about one third of preventable deaths worldwide. Accurate and rapid diagnosis of tuberculosis is essential for controlling the spread of the disease caused by Mycobacterium tuberculosis. The aim of this study was to evaluate the Mycobacteria Growth Indicator Tube [[MGIT 960] [M960]] which is a fully automated, non-invasive, system for growth and detection of mycobacteria and Lowenstein-Jensen [LJ] media for the recovery of Mycobacterium tuberculosis from sputum samples. Out of 67 specimens processed, 60 isolates [89.5%] were recovered by M960 media while, 50 isolates [74.6%] were obtained by LJ. M960 as a single system detected 11 [16.4%] isolates more than L.J media while; L.J media detected 2 [2.9%] isolates [revealed no growth in MGIT 960]. In total, Out of these 67 specimens, 48 [71.6%] were positive by all methods [Z-N smear, culture on both LJ and MGIT broth] and 48 [71.6%] isolates also were obtained by the combined use of both culture methods. Average detection time of M960 and LJ media was 14.6 days [2-38] and 30.6 days [7-58] respectively. The contamination rates in our study were [2.9%] for M960 and [1.49%] for L.J media. In conclusion, comparable to LJ media, M960 system is a rapid and efficient method for diagnosis of pulmonary tuberculosis. But for maximum recovery of mycobacteria, a combination of both M960 and LJ media should be used
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Forty adult male albino rats [200 +/- 20 g each] were used in this study. Animals were equally divided into 4 groups [n = 10]; normal control [CON] group was intraesophageally [i.o.] administered with distilled water [0.5 mL/d] for 1 week [wk]; L-type calcium-channel blocker [CCB] group that i.o. administered with otilonium [octylonium] bromide [OB, 2 mg/kg rat/d dissolved in 0.5 mL distilled water] for 1 wk; a cold-restraint stress [CRS] group that i.o. administered with distilled water as CON group but also restrained for 3 hs/d at 4- 6 degreeC in individual wire-mesh cylinders for 1 wk; and combined group [CCB+CRS group] that i.o. administered with OB as in CCB group and also restrained as in CRS group. The number of fecal pellets expelled by each animal was counted and examined for its consistency every 30 min for 3 hs, starting at 5 min after the induction of CRS or transporting to individual cages. At the end of the 1 -wk period, each rat was sacrificed by stunning and cervical dislocation, the abdominal cavity was opened along the midline, the stomach, upper segment of small intestine [US], lower segment of small intestine [W and a segment from distal colon [DCS] were rapidly excised and soaked in warm [37 degreeC], carbonated Tyrode s solution. Stomach was further used for measuring the areas of erosion [ulcers] if present, while UIS, LIS and DCS were further used for motility study of both spontaneous and evoked contractility in response to ACh and KCl: CRS produced significant increase the spontaneous motility of the UIS when compared to the CON values. Contractile response to ACh and KCl of both UIS and DCS were also significantly increased by CRS. Also, fecal pellet output was increased significantly by CRS when compared with the corresponding values in CON rats. Moreover, CRS induced gastric ulceration which appeared to be scattered along the mucosa of the stomach, On the other hand, the motility of LIS insignificantly changed by CRS. Administration to OB [L-type CCB] produced significant decrease in spontaneous contractions and contractile responses to ACh and KCl of UIS, LIS and DCS, together with decreased fecal pellets output when compared with the corresponding values in CON rats. Administration to OB to CRS rats reduced significantly both spontaneous and evoked motility in response to ACh and KCl of UIS and DCS, while the LIS did not affect significantly when compared with the corresponding values of non-treated CRS group. Also, OB administration reduced significantly the increased fecal pellet output caused by CRS. On the other hand, OB administration to CRS rats produced significant reduction or almost complete protection of the gastric mucosa from the development of ulceration. It can be concluded that OB [L-CCB] could help in prevention and treatment of GIT motility disorders caused by different stressors as CRS. Also, OB could prevent the development of stress gastric ulceration in different forms of stressors
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This prospective study was conducted to evaluate the results of sacrospinalis muscle pedicle bone graft as a method to improve the quality of fusion mass after posterolateral fusion for lumbar sporidylolisthesis. This study included twenty patients with lumbar spondylolisthesis [7 Grade I. 10 Grade II and 3 Grade III]. All patients had low back pain and associated radicular pain was present in 12. All patients failed to respond to adequate conservative treatment. There were 13 females and 7 males. The patients were aged between 25 and 55 years with an average of 37.5 years. Posterolateral spinal fusion with sacrospinalis muscle pedicle bone graft on the left side and autogenous iliac bone chips on the right side with the use of transpedicular internal fixation system, was done in all patients. In 12 patients with radicular pain, laminectomy and discectomy was done in addition. The period of follow up ranged from 8 months to 18 months. Satisfactory osseus fusion was obtained in [85%] of patients on the left side where muscle pedicle bone graft was used while satisfactory osseus fusion was obtained in [70%] of patients on the right side where iliac bone chips were used. Functional improvement was obtained in 90% of patients with excellent to good result. No scoliosis or weakness of the extensor muscles of the back developed after reanchorage of the sacrospinalis muscle to the lumbosacral spines. We recommend the use of sacrospinalis muscle pedicle bone graft to improve the quality of fusion mass obtained in posterolateral fusion for treatment of spondylolisthesis
Subject(s)
Humans , Male , Female , Bone Transplantation , Muscle, Skeletal , Hospitals, UniversityABSTRACT
This study was conducted in an attempt to explore the relationship between the staff nurses [100] perceived job empowerment and their commitment to the organization based on Kanter's structural theory of the organizational behavior. Data were collected from Assiut Health Insurance Hospital [El-Mabarrah] using the demographic data sheet, organizational description opinionaire [ODO], organizational commitment questionnaire [OCQ] and a modified version of the condition of work effectiveness questionnaire [CWEQ]. The results revealed a strong positive relationship between the nurses' perception of access to the opportunities and their commitment to the organization. In addition, the overall empowerment was correlated positively with the nurses' perception of their immediate manager's power