ABSTRACT
Background: speckle tracking echocardiography [STE] enables objective assessment of left ventricular [LV] function through analysis of myocardial strain and strain rate. This study aims to determine the sensitivity and specificity of global longitudinal strain [GLS] and global longitudinal strain rate [GLSR] of LV in assessment of myocardial Jirnction compared to peak wall motion score index [WMSI] at dobutamine stress echocardiography [DSE]
Methods: fifty patients with suspected or known myocardial ischemia were evaluated by conventional echocardiography, DSE, STE and coronary angiography [CA]. Standard apical views were wed to calculate GLS and GHR by STE. WMSI was calculated at peak stress during DSE. Significant coronary lesion[s] were indicated by >/= 50% luminal stenosis in CA
Results: GLS and GLSR were significantly lower in patients with significant CAD than those with
Conclusion: GLS and GLSR are negatively correlated to peak WMSI. Both deformation parameters can predict significant lesion[s] in CA, but with lower diagnostic accuracy than DSE