Is dental interventions safe during pregnancy?

To investigate the safety of tooth extraction and other dental interventions during pregnancy. Pregnant ladies with dental problems were seen by and obstetrician and a dentist. Simple cases were treated medically. Severe cases were identified. When surgical intervention was indicated due to abscess formation or disturbance of sleep, patient consent was taken and the necessary treatment was performed. A contact number was given to each patient and their addresses were taken. All treated patient were asked to report seven days latter for follow up of the dental condition and the pregnancy wellbeing. This study involved 97 pregnant ladies, in different gestational ages, 50.5% of them were in the first trimester. Patients from urban area were 65.9%. The population of this study included patients with pregnancy order up to 8 however 23.7% of them were primigravidae. Some of these ladies [30.0%] gave past history of previous pregnancy complications. Each patient presented with more than two symptoms of the following: pain, disturbance of sleep, difficulty in food chewing, bleeding from the gum and earache. All patients had clinical evidence of infection either pulpitis, gingivitis or both. The main underlining problem of these participants was tooth caries. The surgical dental interventions included; tooth extraction, scaling, filing and root canal treatment. The dental intervention during pregnancy using local anaesthesia is safe. The severe pain, difficulty of feeding and disturbance to sleep due ora/dental diseases may cause more danger to mother and her fetus than dental intervention

Pregnancy after treatment of choriocarcinoma - case Report

This is the first case report from its kind to be reported from the Institute of nuclear medicine, Molecular Biology University of Gezira. It is a case report of a 30-years old lady diagnosed as having choriocarcinoma, gestational trophoblastic tumor, and treated with multiple agent chemotherapy for three months. She was advised not to get pregnant during the first two years following chemotherapy. She was on regular follow up for one year after which she disappeared and discontinued the contraceptive pills. Seven months later she presented with a viable pregnancy and was followed till she delivered a normal viable alive boy. Both the lady and her baby are in a good health after six months from delivery

Gynecological malignancies managed in the institute of nuclear medicine and oncology, wadmedani-Sudan during 1999-2005

Gynecological malignancies [GMs] are one of the most prevalent cancers in Africa. Objective of this work is to review data of patients with GMs treated in Institute of Nuclear Medicine, Molecular Biology and Oncology [INMO]-University of Gezira -Wadmedani- Sudan, and reflect on characteristics of GMs in Central Sudan. A retrospective hospital-based descriptive study was conducted to review GMs patients records treated in TNMO from year 1999-2005. Analysis included age, residence, stage, topography and morphology of the cancer. During study period GMs constituted about 20.5 percent of all women malignancies and it is the second commonest female cancer preceded by breast [36.7%]. Most of the patients were housewives from rural areas of Gezira and nearby States. The sites were ovary, 41%, cervix, 34%, uterus, 13.8%, uterine choriocarcinoma, 7.9%, vulva cancer, 2.9% and no single case of vaginal carcinoma was reported. The mean age of all patients was 52.45 years, Median age for ovarian cancer was, 50, cervix 55, uterus 55, Choriocarcinoma of the uterus 35 and vulva 60 years of age. Almost all varieties of histopathological types were seen. Fifty eight percent of patients presented with stage III and IV. GMs are common and present in late stages, The commonest OMs was ovarian cancer which affect relatively young patients. Cervix was the second common site and affect relatively older age group. Vulvar cancer was relatively rare and vaginal cancer was not seen. For the improvement of the outcome early detection, management guidelines and financial support are highly recommended

Genotyping of toxoplasma gondii strains in pregnant women with toxoplasmosis in Gezira state, central Sudan

To perform genotyping of Toxoplasma gondii among pregnant women with toxoplasmosis in Central Sudan. The study group was presented by 94 pregnant women who had abortion between the second and fourth months of gestation, whereas the control group consisted of 64 full term normally delivered women. The study was conducted at Wad Medani Teaching hospital, Gezira State, Central Sudan during the period of March 2002 to May 2004. PCR test on aborted and placental tissue revealed positivity rate of 19.1% and 22.3%, in study and control groups respectively, with no significant difference between them [P=0.55]. This compared to a seroprevalence rate of 35.1% and 39.4% in study and control groups respectively. Genotyping form clinical samples using PCR/RELP revealed Toxoplasma gondii type II in 89% and 95% of the study and control group respectively, whereas, 11% and 5% were infected with type III. The most prevalent strain of T. gondii among the pregnant women was Type II followed by type III but type I was completely absent

Epidemiologial studies on toxoplasmosis in pregnant women using serological methods in Gezira state-central Sudan

To study the relationship between toxoplasmosis and the outcome of pregnancy [full term and abortion] and to find out the epidemiological risk factors. This case control study was carried out at Wad Medani Teaching hospital, Gezira State, Central Sudan during the period March 2002-May 2004. The cases were 100 pregnant women who presented with abortion between the second and fourth months of gestation, and the controls were 100 full term normally delivered ELISA lgG test [n = 94 in each group] revealed 35.1% and 39.4% seroprevalence rates in the study and control groups respectively with no significant difference [p=0.6]. When performed on IgG seropositives, ELISA IgM seroprevalence rates were 15.2% and 16.2%, in the study and control groups respectively. Statistically, there was no significant difference between them [p=0.9]. When correlated to sociodemographic characteristics and risk factors, Toxoplsma gondii seroprevalence showed significant relationship for age, education, occupation, parity and past history of congenital malformations in both groups. There was significant difference between the two groups for ethnicity. The most important risk factor in both groups was the intake of raw meat [herbivorous viscera]. The findings of this study suggests that, ingestion of infected raw meat is an important risk factor for toxoplasmosis. [OR, 3.87; 95%CI, 1.59-9.44] in the study group, while in the control group [OR, 4.41; 95%CI, l.76-11.09]