ABSTRACT
TRUS is the preferred ultrasonic investigation of BPH and other prostatic diseases providing a safe, non-invasive technique for imaging of the prostate. The size of the prostate can be measured, also staging and screening of prostatic cancer. TRUS is an ideal imaging modality for follow-up of patients treated for cancer prostate and infection permitting sequential objective assessments of the gland texture and capsular integrity. In combination with PSA measurements and DRE it may be useful for detecting prostatic cancer and screening programs based on TRUS. PSA. and DRE, that combination can be used in clinical trials of different treatment regimens for prostatic cancer. However microscopic invasion the prostatic capsule and cancers less than 4.4 mm, also false positive results as a result of similar echogenicity of normal structure and some lesions, and lastly isoechoic cancers are main limitation of TRUS evaluation of prostatic lesions