Retinal damage by infra-red radiation

Albino rats were exposed to infra red radiation of 800 Watt power. A daily exposure of one hour was performed and the eyes were enucleated and examined histologically and electron microscopically after 1, 2 and 3 months. The morphological changes which occurred during this period in the different layers of the retina were discussed

Reversal of postcastration atrophy of rabbit prostate by testosterone treatment

A histological and histochemical studies of the prostate gland were carried out in rabbit by light microscopy. Fifteen adult male tame rabbits were used. The animals were divided into three groups, five animals each. The control animals were of the first group. In the second and third groups the rabbits were castrated. One month after castration the animals of the third group were injected daily by testosterone propionate [1 mg/100 Gm body weight] for one month. The prostate was observed 45 days after castration. The gland became smaller in size and showed marked histological atrophic changes, such as great diminution in the size of the acini, narrowing or obliteration of their lumens, distortion of the lining epithelial cells and marked reduction in the number of the epithelial folds. The epithelial atrophic changes were accompanied by loss of secretory granules and marked decrease of acid phosphatase activity. Also, this marked atrophy of the glandular tissue was accompanied by increase of fibromuscular stroma. In castrated, testosterone treated group, it was found that the size of the whole prostate was reversed to the normal size. Also, testosterone administration restored the normal histological and histochemical structures of the prostatic epithelial cells. Moreover complete restoration of the activity of the gland was achieved by testosterone treatment. From our study on the rabbits as well as from previous studies by other workers on the rats and mice, it could be concluded that castration of the experimental animals induced prostatic atrophy which could be reversed by testosterone treatment