Subconjunctival steroid for pearls like tumour in the anterior chamber of the eye

Pearl like tumor in the anterior chamber of the eye is a not uncommon affection of children eyes, difficult to tract by topical and/or systemic steroid assuming that the condition is allergic in origin. To assess the effect of sub-conjunctival steroid injection in these cases. It is a retrospective study for all patients aged between 10 - 18 years presenting with a unilateral grayish white nodule at the angle of the anterior chamber of the eye sub-conjunctival long acting steroid was given for all patients and the follow up was done for one year. 10 eyes of 10 patients were included in this research. One child was a new case and 9 were recurrent cases. All 10 then had varying degree of anterior ureitis. After steroid injection the severity of iritic decreased in all patients. The size of the lesion decreased to more than 50% after 2 months. sub-conjunctival steroid injection for pearl like lesion in the anterior chamber of the eye is a safe and effective way of treating such lesion

Study of soluble thrombomodulin as an early marker of endothelial cell injury in obese children

Obesity in children is associated with various cardiovascular risk factors as well as an increased cardiovascular disease morbidity and mortality in adulthood. Thrombomodulin, a glycoprotein with vasoprotective and anticoagulant properties, is located at the luminal endothelial cell surface. Its soluble form results from endothelial cell injury. The aim of this work was to study thrombomodulin as an early marker of endothelial cell injury in obese children. This study was done on 40 children: 20 obese and 20 non-obese control children. They were subjected to clinical examination and the following investigations, CBC, blood urea and serum creatinine, fasting blood glucose, serum cholesterol serum triglyceride, HDL-cholesterol, LDL- cholesterol and soluble thrombomodulin by ELISA. There was significant increase in blood pressure, fasting blood glucose, cholesterol, LDL-cholesterol, triglycerides and soluble thrombomodulin in obese children compared to control group [p < 0.05]. HDL-cholesterol was significantly lower in obese children compared to non-obese ones [p < 0.05]. There was significant positive correlation between blood pressure and plasma soluble thrombomodulin. From this study it could be concluded that obese children had more elevated blood pressure, fasting blood glucose and dyslipidemia. Soluble thrombomodulin was higher in obese children compared to controls. It was positively correlated with elevated blood pressure denoting endothelial cell injury in obese children

Mechanical and thermal properties of hydroxyaptite filled poly (methyl methacrylate) heat processed denture base material

The aim of this study was to evaluate the effect of powder-to-liquid ratio on the glass transition temperature (Tg) and the tensile properties of denture base material prepared from poly (methyl methacrylate) (PMMA) and hydroxyapatite (HA) previously treated with 3-trimethoxysilylpropyl methacrylate (gamma-MPS). Specimens for mechanical testing were prepared by adding composites powder (PMMA, BPO and HA) to the monomer (MMA and EGDMA) followed by hand mixing as in dental laboratory description usage. The glass transition temperature was studied by using differential scanning calorimetry (DSC). It was observed that the tensile properties and the Tg were affected by the powder-to-liquid ratio. The mechanical characterization of the materials were performed by using single edge notch-tension (SEN-T) specimens; the fracture toughness was slightly higher in formulation which contained HA filler compared to commercial denture base material.

Hernioabdominoplasty: evaluation of the technique in relation to respiratory functions

This study was carried out on 15 adult females admitted with moderate to severe obesity and having ventral hernias with variable degrees of panniculus adiposus with body mass index [BMI] ranging between 28 - 35 kg/m 2. Patients were classified according to the abdominoplasty system of classification and treatment to fit types III and IV for surgery and according to the ASA I or II classification for anesthesia. The tightness of the repair was adjusted according to the airway pressure of the patient. An airway pressure of 3 - 7 cm water increase was allowed. Ellipses of dermolipic segments removed ranging between 7 - 12 kg. The lung volumes [VC, IC, ERV, TLC and FRC] showed significant decrease on the first and third postoperative day and returned to the preoperative values on seventh day. RV decreased only on the first postoperative day. Spirometric functions [FVC, FEV, PEFR, FIVC, FIFR and MVV] showed significant decrease all through, although showed gradual return to preoperative values. In the pattern of ventilation there was a significant increase in respiratory rate and a significant decrease in tidal volume. Blood gas changes showed that PaO2 showed significant decrease which was subclinical. SaO2 showed a significant decrease on the first postoperative day with no significant change on the 3rd and 7th days. PaCO2, pH and BE showed no significant changes

Assessment of neutrophil function in localized pre-pubertal periodontitis

Polymorphonuclear leucocytes [PMNS] from L-PP patients revealed variousdegrees of functional defects. This study was undertaken to investigatechemotaxis, phagocytosis and intracellular killing Poer of PMSs in L-PP agematched controls and adult controls. Peripheral blood PMNs from a total of 6patients with L-PP, 6 age matched pediatric controls, and 5 adult controlswere analyzed for neutrophil function. The results showed that chemotaxis ofPMNs from both L-PP patients and pediatric controls was nearly at the samelevel, but significantly depressed compared to adult controls. There was nosignificant difference between chemotaxis of PMNs from L-PP patients and thatfrom age matched controls. On the other hand, both phagocytosis andintracellular killing power of PMNs from patient with L-PP were matchedcontrols or adult controls. It seems from the results of this study thatneutrophil function in L-PP patients is defective as regard to phagocytosis,intracellular killing but not for chemotaxis

Some late major complications after Austin Moore unipolar replacement arthroplasty for fracture neck femur practical considerations

Austin Moore's replacement hemiarthoplasty is accepted safe procedure for early weight bearing. It is advocated for elderly patients to avoid prolonged disability, repeated operations and to improve the function. The aim of the study was determination of the durability of the hip after replacement through representing some of the important late major complications comporomising the functional end result. The study was done for 136 patients underwent for Moore's head replacement after fracture neck femur. The complications was evaluated for available 84 patients for an average 42 months follow-up period. Some late complications present in 31 patients [36%] was discussed. Successful functional outcome was significantly reduced after major complications. The incidence of complications increased with delayed operation and with prolonged follow-up period. This was related to incompatability between metal and bone and to diminished vitality of the patient. Roentogenograms was utilized in an attempting to explain the causes of failure. The mortality rate [23%] exceeded the percentage expected for this age group, and this was related to associated cardio pulmonary diseases. Late complications did not vary much with sex incidence but were related to the condition of the acetabulum existed at the time of replacement. Early local complications within the first months were superficial infection [9%] [13 cases], deep sepsis [3% [5 cases]], malposition [4% [6 cases]], dislocation [5% [7 cases]], fracture femur [8% [II cases]], deep vein thrombosis [5% [7 cases]], peroneal nerve palsy [2% [3 cases]]. More than one complication occurred in 37 patients. Late complications encountered were 8.3% loosening of the femoral stem [7 cases], 5.9% distal migration [5 cases], 8.3% interosion of the head in the acetabulum [7 cases], 8.3% deep sepsis [7 cases], 3.6% late dislocation [3 cases], 2.3% ankylosis [2 cases], 7.2% fracture femur [6 cases], 21.4% ankylosis [2 cases], 7.2% fracture femur [6 cases], 21.4% idiopathic pain [18 cases], 53.6% limited movement [45 cases], 72.6% limping [61 cases]. 4.6% sittling [39 cases], 17.8% idiopathic osteoporosis [15 cases] and 4.8% pararticular ossification [4 cases]. The major late complications were loosening, distal migration, interosion, deep sepsis, late dislocation, ankylosis and fracture femur. Combination of complications was present. Mobility was related to the preoperative range in the hip. Low seating of the prosthesis and spesis caused the high incidence of dislocation. Ten prosthesis [11.9%] was removed because of sepsis and mechanical instability. There was no correlation between deep infection and posterior approach but sepsis was related to incontenance [5.9%]. Dislocation was also related to inappropriangth and head size. Late pain was related to various causes most important was protrusion-acetabuli. Its incidence was diminished by reducing the friction wear of the articular cartilage by long partial weight hearing. Pain and defective weight bearing capacity were related to boring the head of the prosthesis in the relative unhealthy acetabulum as was noticed at the time of insertion of the prosthesis. Also, pain was related to aseptic loosening which predominated in the relatively young and active patients. Limping [72.6%] with trendelenburg gait was related to muscular insufficiency, to neck shortening, and to tendency for settling which increased with age. There was no correlation between severity of the symptoms and the radiological signs of bone resorption, prosthetic loosening, settling or wandering acetabulum. Marked bone resorption was related to latent infection or aseptic loosening which became more apparent with prolonged follow-up period. This study for complications suggest that the principle indication for prosthetic replacement should be non-union and avascular necrosis complicating high fracture neck femur. It also suggest limitation of replacement in acute displaced neck fracture because replacement provide only a temporary solution to part of the problem by early mobilization but function never equal normal and difficult complications occur even when patients were chosen with caution and the prosthesis was inserted with skill because of the specific problems related to the prosthesis [especially in the physically vigorous patients] in addition to the inherent complication in hip surgery. Subsequently, the choice of the method treatment should be highly individualised and not based on the physiological age alone. There is no need to expose all patients to the increased risk of the more hazardous revision operations. This study also suggest protection of the medial femoral cortex from compression strain during the first months [to minimise the incidence of complication and to allow for microfracture bone healing] while was achieved by long use of cane