ABSTRACT
Introduction: Hypertension is very common conditionamong adult and elderly patients. Ii is one of the importantrisk factor of atherosclerosis of vessels. Anesthetist’s morecommonly tackle the management of treated and untreatedhypertensive patients. The considerable concern of anaesthtistnot only strong association with coronary artery disease butpotential target organ damage. This study was conducted toassess cardiovascular response in different stages of generalanesthesia in abdominal surgeries.Material and methods: Sixty adult patients undergoingdifferent elective abdominal operations under generalanesthesia were included. Patients were divided into A andB group. A group consists of normotensive patients while Bgroup consists of controlled hypertensive patients. Their bloodpressure were controlled on single antihypertensive drug.B group further divided into B1 and B2. B1 group patientswere on beta blockers (BB) while B2 group patients were onangiotensin converting enzyme inhibitors(ACEI).Results: There was decrease in SAP, DP and HR in all groupsafter induction while there was increase in SAP, DP and HRin all groups after laryngoscopy and intubation. There wasminimal rise in SAP, DP and HR in all groups during surgery.The rise of HR was comparatively less in BB group thanACEI group during laryngoscopy and intubation while rise inSAP was comparatively more in ACEI than BB group duringsurgery.Conclusion: On the basis of the present observation it canbe concluded that pressure response and cardiac response(cardiovascular response) to laryngoscopy and intubationappears to be unaffected with these antihypertensive drugs.
ABSTRACT
The aim of study was to investigate differences in clinicopathological [CPC] features of colorectal cancer [CRC] patients between both genders. We did a retrospective chart review of CRC patients confirmed by histopathology. 414 patients were included in study from King Abdul Aziz medical city Jeddah. Charts of patients were reviewed; data was analyzed on SPSS version 20. Majority of patients were males [58.7%] who were slightly older than females [mean age 57.7 versus 54.6 years] [p value 0.033]. The most common age group was fifty to eighty years in both genders [64% patients]. Abdominal pain was reported more in females [57% vs. 41.5% p value 0.002] while there was no difference in reporting bleeding per rectum between both genders [50.2% vs. 49.3% p value 0.953]. History of diabetes mellitus [DM], smoking and colonic polyps] was more common in males [67 versus 34 patients], [21 versus 3 patients] and [10 versus 1 patient respectively. Patients presenting with acute surgical abdominal complications were less than 20%. Only 33 [19.2%] of females received preoperative chemotherapy vs. 80 [33%] of males [p value 0.001]. There was no significant gender differences regarding site, histopathology grade and surgical treatment received. There are important gender differences in CPC features of CRC patients in our population. Female patients tend to be slightly younger than males and there is less association with smoking, DM and previous colonic polyps. Abdominal pain was the most common presenting symptom among females. Both genders presented at similar stage of disease. These observations should be taken in consideration in making colorectal screening guidelines and public awareness programs
Subject(s)
Humans , Male , Female , Colonic Polyps , Sex Factors , Retrospective StudiesABSTRACT
The purpose of present study is to compare anthropometric characteristics of the adult cranium between Iranian and Pakistani residents in two specific areas where people have special characteristics in the features of their heads and faces. This cross-sectional investigation was performed on 300 adult inhabitants of Qazvin, Iran and 356 residents of Dera Ghazi Khan, Pakistan. Participants were selected randomly and did not have any physical deformities or any previous history of trauma. Measurements were performed in an anatomical position on the cephalic length, cephalic breadth, and auricular height. Cephalic length, cephalic breadth and auricular height in females from Qazvin were significantly higher than those of DG Khan [p<0.05]. According to the findings, 82% of males and 58% of females from Qazvin were megacephalic while 25% of males and only 1% of females of DG Khan were megacephalic. The prominent cranium from in males from DG Khan was mesocephaly [41%], whereas it was microcephaly [85%] in females from DG Khan. The mean cephalic index was as follows: Qazvin males [88.19 +/- 5.78] and females [86.54 +/- 3.23]; DG Khan males [84.11 +/- 3.7] and females [85.27 +/- 6.09]. For DG Khan residents, the cranial capacity was 1348.4 +/- 122 cm[3] for males and 1189.3 +/- 180.5 cm[3] for females. At the same time, the brain weight was 1395.5 +/- 126.2 g in males and 1230.9 +/- 186.8 g in females. This study shows the existence of differences in cranium dimensions between residents of Qazvin, Iran and DG Khan, Pakistan as well as in different regions of each country