ABSTRACT
Aim of the Study: was to investigate the influence of phacoemulsification on corneal endothelial cells and its injury risk factors in diabetic cataract patients and non-diabetic patients
Methods: Electronic databases were searched: Scopus, EMBASE, and Google Scholer], PubMed/MEDLINE, Scopus, The Cochrane Library, and Web of Science. Econlit from 1990 to 2017. This was completed with a manual search of references of relevant papers. Risk of bias in methodology of studies was measured using the Newcastle-Ottawa Scale
Results: Observation of corneal endothelial cell density, coefficient of variation and percentage of hexagonal cells preoperatively, 1 day, 1week, 1 and 3 months postoperatively was carried out, and multiple Logistic regression analysis for risk factors of corneal endothelial cell injury was taken
Results: Out of 779 retrieved papers, 9 studies with a total of 1129 individuals were finally included [579 diabetic eyes and 550 non-diabetic eyes]. For the dynamic changes between preoperative and postoperative values, significant differences were identified between the two groups in endothelial cell density [ECD] and hexagon cells [HC%] at 1 day, 1 week, 1 month, and 3 months postoperatively, in central corneal thickness [CCT] at 1 month postoperatively, and in coefficient variation [CV] at 1 week and 1 month postoperatively. However, no significant differences were observed in CCT at 1 day, 1 week and 3 months postoperatively or in CV at 1 day and 3 months postoperatively
Conclusion: It could be concluded from the current literature that aged-cataract patients with diabetes mellitus manifested poor tolerability to cataract phacoemulsification surgery in contrast to senile cataract patients
ABSTRACT
Background:Spontaneous gastric perforation is usually a complication of peptic ulcer disease, or a postoperative complication resulting from gastric torsion. Mucormycosis [or zygomycosis] is an uncommon opportunistic fungal infection that is usually seen in immunocompromised patients and is associated with significant morbidity and mortality. This report is of a rare case of spontaneous gastric perforation due to mucormycosis infection
Case Report:A 52-year-old woman, with a past medical history of heroin abuse, diabetes mellitus, hypertension, and chronic kidney disease treated by dialysis, presented to the emergency department with cellulitis of the arms. Following hospital admission, her medical condition deteriorated, and she developed septic shock and multiorgan failure, requiring transfer to the intensive care unit [ICU], where she was diagnosed with a perforated hollow viscus as the cause. Surgical exploration showed that the mucosa of the stomach was necrotic and perforated, but the remaining bowel appeared normal. Total gastrectomy was performed, and a jejunostomy feeding tube was inserted. Histopathology of the gastric tissue confirmed infection with mucormycosis. The patient was treated with adjunctive liposomal amphotericin B, her condition improved, and she was extubated on postoperative day 2. However, the patient died on postoperative day 21 due to sepsis and multiorgan failure
Conclusion:Mucormycosis is an opportunistic angioinvasive fungal infection, and gastric perforation is a rare clinical presentation. However, knowledge of the association between gastric necrosis and perforation and mucormycosis infection might lead to early diagnosis and treatment and reduce patient morbidity and mortality
ABSTRACT
Background: A substantial group of patients with gallstone disease experience negative outcome after surgical removal of the gallbladder [cholecystectomy]. Early identification of these patients is important
Purpose: The purpose of the study was to recognize predictors [trait anxiety and clinical symptoms] of negative symptomatic outcomes at 5 weeks after cholecystectomy
Materials and Methods: Consecutive patients [n=66], 18-60 years, with symptomatic gallstone disease, completed symptom checklists and the state-trait anxiety inventory preoperatively and at 6 weeks after cholecystectomy. Results: High trait anxiety was the only predictor of persistence of biliary symptoms at 6 weeks after cholecystectomy [OR=6.79]
Conclusion: In addition to clinical symptoms, high trait anxiety is a predictor of negative symptomatic outcome at 6 weeks after cholecystectomy. Trait anxiety should be evaluated to aim at a patient-tailored approach in gallstone disease