ABSTRACT
This study was conducted at Pathology Laboratory, Combined Military Hospital, Quetta to evaluate susceptibility patterns of Methicillin Resistant Staphylococcus areus [MRSA] to commonly used anti staphylococcus antimicrobials during the period April 1996 to November 2000. One hundred consecutive, non-duplicate strains of MRSA isolated from different clinical samples were identified by standard microbiological methodology. They were studied for their susceptibility to co-trimoxazole, erythromycin, tetracycline, gentamicin, chloramphenicol, ciprofloxacin, fusidic acid and vancomycin by disc diffusion technique using modified Kirby-Bauer method. All the MRSA were sensitive to vancomycin. Four% strains revealed resistance to fusidic acid, 62% to chloramphenicol, 79% to ciprofloxacin, 80% to gentamicin, 88% to erythromycin 93 to tetracycline and 97% to co-trimoxazole. Most of the MRSA were multidrug resistant. These strains revealed higher degree of resistance [>60%] to routine anti-staphylococcus anti microbials. Vancomycin and fusidic acid could be life saving anti-staphylococcus antimicrobials in MRSA infections in Quettta