ABSTRACT
Background: Ulcers and surgical wounds not healing well andexpectedly are common problems among patients in countrieslike us. Ulcers may develop spontaneously or following apenetrating injury. Wounds not healing well are commonamong poor, lower middle class and middle class people.Postsurgical non-healing wound or chronic discharging sinusesat the scar site are also common in that class of people.Suspecting malignancy or tuberculosis in these types ofwounds we have sent wedge or excision biopsy for theseulcers in about 500 cases and found tuberculosis in 65 cases.In rest of the cases histopathology reports found as nonspecific ulcers, malignant melanoma, squamous or basal cellcarcinoma, Verruca vulgaris.Objectives: To find out the relationship of tuberculosis withchronic or nonhealing ulcers.Methods: This is a prospective observational study conductedfor patients coming to our chambers, OPD of a district generalhospital and Shaheed Suhrawardy Medical College Hospital,Dhaka.Results: Mean age of the study subjects were 28±2. Amongthe study subjects nonspecific ulcer or sinus tracts were foundin 418 (83.6%), tuberculosis in 65 (13%), Malignant melanoma7 (1.4%), Verruca vulgaris 5 (1%), squamous cell carcinoma3(0.6), basal cell carcinoma 2 (0.4%). Biopsy done only forvery suspicious ulcers or wounds.Conclusion: With this very small sample size it is difficult toconclude regarding incidence of cutaneous involvement ofextra pulmonary tuberculosis, but every clinician should think ofit in case of suspicious non healing wounds, ulcers andprolonged discharge from a surgical incision site.
ABSTRACT
Background: This have a look at evaluated the position oflaparoscopic surgical procedure is the early control of acutegallbladder disease among a hundred and twenty patients inShaheed Suhrawardy Medical College Hospital and PrivateClinics of Dhaka City.Methods: Information of all emergency admissions for acutegallbladder diseases from March 2014 to June 2016 wasidentified and additional data from the hospital facts becomereviewed retrospectively.Results: Hundred and twenty students are gallbladder disease(87 patients presented with acute biliary pain and 33 patientspresented with acute cholecystitis). The conversion rate turnedinto better throughout early laparoscopic surgical treatment foracute calculous cholecystitis than in operations for acute biliarycolic. In sufferers with acute calculous cholecystitis theconversion charge turned into extensively lower in operationswithin 48 hour of admission than when surgical procedurebecome not on time past 48 h or ultimately carried outelectively.Conclusion: Laparoscopic cholecystectomy for acutegallbladder diseases should be performed well and givepositive feedback after the surgery.
ABSTRACT
This study was on the molecular characterization of Harnai sheep breed in Balochistan. A set of (n=16) ovine specific SSR markers, recommended by FAO, was used on (n=50) blood samples from unrelated animals of Harnai sheep breed from their breeding tract. Various genetic parameters were observed using Pop gene software. A total of 74 alleles were found on 13 loci. The finding values for observed number of alleles (Na), effective number of alleles (Ne) and Shannon’s Information index (I) the average values were found along with standard deviation to be 2.448±0.869, 1.7050.604 and 0.5890.357 respectively, further more, the mean values of observed heterozygosity (Obs_Het) expected homozygosity (Exp._Hom), expected heterozygosity (Exp_Het), effective number of allele (Ne) average Heterozygosity (Ave Het) were found to be 0.598±0.299, 0.366±0.284, 0.602±0.238, 0.363±0.219, 0.347±0.209 and 0.347±0.209, respectively. The value of F-statistic ranged from 0.2851 to 0.9132 for different microsatellite markers with an average of 0.515±0.021. Majority of the markers showed higher than average expected reduction in heterozygosity. The standard errors were generally low, which indicated that homozygosity prevails in the population under study. This might be due to intense inbreeding in this flock of Harnai sheep.