ABSTRACT
Regular moderate intensity physical activity and lipid lowering effects of Nigella sativa [N. sativa] supplementation may be appropriate management for sedentary overweight females. Therefore, the aim of the present study was to examine the effects of long-term N. sativasupplementation and aerobic training on lipid profile and maximal oxygen consumption [VO2max] in sedentary overweight females. In this randomized, double-blind, controlled trial, which was conducted in Kerman city [Iran], 20 sedentary overweight females were divided into two groups and assigned to N. sativasupplementation [N. sativacapsules] or a placebo for the 8 weeks, both groups participated in an aerobic training program [3 times/week]. Each N. sativacapsule contained 500 +/- 10 mg N. sativacrushed seeds and subjects had to take 2 g N. sativaperday for 8 weeks. Blood lipids and VO2 max were determined at baseline and at the end of 8 weeks. N. sativasupplementation lowered total cholesterol [TC] [P< 0.01], triglyceride [P< 0.001], low-density lipoprotein [LDL] [P< 0.001] and body mass index [P< 0.01] and increased high density lipoprotein [HDL] and VO2 max [P< 0.01]. Aerobic training program lowered TC [P< 0.001] and LDL [P< 0.01] and increased VO2 max [P< 0.01]. Furthermore, we observed a significant effect of aerobic training program and N. sativasupplementation lowered LDL and HDL [P< 0.05]. The present study demonstrates that 8-week aerobic training plus N. sativasupplementation have a synergistic effect in improve profile lipid parameters
ABSTRACT
Probably L-Carnitine can induce increasing of Pyruvate dehydrogenase activity, decreasing of lactic acid production and performance improvements due to the reinforcement of long chain fatty acid oxidation and stabilize of Coenzyme A [CoASH] to free Coenzyme A [COA]. Based on this, the aim of this study was to investigate the effect of acute L-Carnitine supplementation on blood lactate, glucose, VO[2max] and anaerobic power in trained men. Sixteen trained men [aged 19-23] volunteers from University of Guilan, faculty of Physical Education and Sport Sciences participated as subjects in this investigation. Subjects divided to aerobic [A] and anaerobic [An] group randomly. In a double blind design, subjects participated in two separated tests by one week. Subjects ingested 3 grams of L-Carnitine supplementation or placebo [maltodextrin] 90 minute before aerobic and anaerobic exercise. For aerobic activity used shuttle run 20 meter and for anaerobic activity used RAST test. Blood samples were collected 5 minute prior at rest and 4 minute post tests. Participants were asked in the morning to obtain fasting blood samples and perform tests. A t-test was used to detect differences between supplementation and placebo groups in each exercise. L-Carnitine group [[A] 141.25 +/- 20.62 and [An] 145.38 +/- 55.47] significantly had lower lactate concentration than placebo [[A] 151.00 +/- 20.85 and [An] 152.50 +/- 28.59] after tests [P