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1.
Pakistan Journal of Pharmaceutical Sciences. 2013; 26 (6): 1165-1172
in English | IMEMR | ID: emr-148547

ABSTRACT

Six compounds have been isolated from methanolic and petroleum ether extracts of Berberis lyceum [Barberry]. Four out of six isolated compounds are reported for the first time from this plant. Purification of different compounds has been accomplished by conventional extraction and chromatographic techniques. The compounds have been structurally characterized by IR, Low Resolution MS, [1]H-NMR and [13]C-NMR spectroscopic techniques. All plant extracts and isolated compounds were assayed for the first time for their antioxidant activity


Subject(s)
Phytochemicals , Antioxidants , Plant Extracts
2.
Pakistan Journal of Pharmaceutical Sciences. 2010; 23 (3): 349-357
in English | IMEMR | ID: emr-98184

ABSTRACT

Fungi, in particular, are able in common with the higher plants and bacteria, to produce metabolites, including alkaloids. Alkaloids, along with other metabolites are the most important fungal metabolites from pharmaceutical and industrial point of view. Based on this observation, the authors of this review article have tried to provide an information on the alkaloids produced by the species of genera: Boletus, Fusarium and Psilocybef from 1981-2009. Thus the review would be helpful and provides valuable information for the researchers of the same field


Subject(s)
Basidiomycota/metabolism , Psilocybe/metabolism , Fusarium/metabolism
3.
Pakistan Journal of Pharmaceutical Sciences. 2010; 23 (2): 175-177
in English | IMEMR | ID: emr-98350

ABSTRACT

To examine the serum antioxidant levels like vit-C, vit-E and glutathione in patients with renal diseases who were subjected to dialysis and to evaluate the antioxidant by FRAP method. To find out the involvement of free radicals in pathogenesis of renal disease. Fifty patients with high levels of creatinine and urea level were included in the study of dialysis. A difference of antioxidant level of vit-C, vit-E and glutathione was observed. The study therefore suggests the importance of assessing these marker oxidative stress antioxidant capacities in renal disease during dialysis


Subject(s)
Humans , Middle Aged , Aged , Adult , Renal Dialysis/adverse effects , Blood Chemical Analysis/methods , Kidney Failure, Chronic/blood , Creatinine/blood , Ascorbic Acid/blood , Oxidative Stress , Vitamin E/blood
4.
Pakistan Journal of Pharmaceutical Sciences. 2010; 23 (1): 48-52
in English | IMEMR | ID: emr-93406

ABSTRACT

Use of Kohl [Surma] creates toxicity or protects eye, is one of the most controversial topic of modern medicines. However, modern researches show that kohl forms a thin film on the eye lens thus avoiding the direct contract of harmful UV radiation and glare of sun with lens. Black and shining particles of galena in kohl shield the eyes from glare and reflection of sun and thus protect them from harmful effect of UV radiation emerging from the sun. Based on these findings and other properties of kohl, it was decided to undertake this study to ascertain it's chemical composition and to correlate these properties scientifically. In the present study, kohl stone obtained from Madina [Saudi Arabia] was analyzed to ascertain it's chemical composition. The chemical analysis and X-ray diffractometer results obtained, showed that the main component of kohl stone is galena [PbS]


Subject(s)
Sulfides/chemistry , X-Ray Diffraction , Arabs , Islam
5.
Pakistan Journal of Pharmaceutical Sciences. 2010; 23 (1): 119-124
in English | IMEMR | ID: emr-93418

ABSTRACT

More than 2000 plants have been listed in the Traditional [Herbal/Alternative] systems of medicine and some of these are providing comprehensive relief to the people suffering from cardio-vascular diseases, specially [hyperlipidemia] and [ischemic heart disease]. WHO reports indicate that around eighty percent of the global population still relies on botanical drugs and several herbal medicines have advanced to clinical use in modern times. Based on these findings, present review is written to identify the [Pharmacology and Cardio-vascular Application] of four commonly used plants in Pakistan. These include, Crataegus oxycantha, Inula racemosa, Terminalia arjuna and Commiphora mukul The selection of the plants in the present study is primarily based on their chemistry and pharmacological properties including toxicology reported in various research articles and reviews. Some very interesting findings have been observed and thus recorded and reported in this review


Subject(s)
Humans , Cardiovascular System/drug effects , Plant Extracts , Cardiotonic Agents , Evidence-Based Medicine , Phytotherapy , Plants, Medicinal
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